HAMAP logo

HAMAP rule MF_00609

Send feedback

General rule information [?]

Accession MF_00609
Dates 10-DEC-2002 (Created)
14-MAY-2022 (Last updated, Version 23)
Name Pyridoxal_decarbox
Scope(s) Bacteria
Template(s) P05034 (DCHS_MORMO); P19113 (DCHS_HUMAN); [ Recover all ]
Triggered by HAMAP; MF_00609 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DCHS
Protein name RecName: Full=Histidine decarboxylase;
Gene name Name=hdc;

Comments [?]

CATALYTIC ACTIVITY Reaction=H(+) + L-histidine = CO2 + histamine; Xref=Rhea:RHEA:20840, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57595, ChEBI:CHEBI:58432; EC=;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
SIMILARITYBelongs to the group II decarboxylase family.

Keywords [?]

Gene Ontology [?]

GO:0004398; Molecular function:histidine decarboxylase activity

Cross-references [?]

Pfam PF00282; Pyridoxal_deC; 1;

Features [?]

From: DCHS_KLEAE (P28577)
Key From To Description Tag Condition FTGroup
BINDING 120 120 /ligand="substrate" H
MOD_RES 233 233 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 369-405 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)