HAMAP rule MF_00609

General rule information [?]

Accession	MF_00609
Dates	10-DEC-2002 (Created) 14-MAY-2022 (Last updated, Version 23)

Name	Pyridoxal_decarbox

Scope

Bacteria

Templates

P05034 (DCHS_MORMO); P19113 (DCHS_HUMAN): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

DCHS

Protein name

RecName:		Full=Histidine decarboxylase;
		Short=HDC;
		EC 4.1.1.22;

Gene name

hdc

Comments [?]

Catalytic activity	RHEA:20840: H(+) + L-histidine = CO2 + histamine EC 4.1.1.22
Cofactor	pyridoxal 5'-phosphate
Subunit	Homotetramer.
Similarity	Belongs to the group II decarboxylase family.

Keywords [?]

Gene Ontology [?]

GO:0004398; Molecular function: histidine decarboxylase activity.

Cross-references [?]

Pfam	PF00282; Pyridoxal_deC; 1;
PROSITE	PS00392; DDC_GAD_HDC_YDC; 1;

Features [?]

From: DCHS_KLEAE (P28577)

Key From To Description Tag Condition FTGroup

BINDING 120 120 /ligand="substrate H

MOD_RES 233 233 N6-(pyridoxal phosphate)lysine K

Additional information [?]