HAMAP rule MF_00609
General rule information
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| Accession | MF_00609 |
| Dates | 10-DEC-2002 (Created)
14-MAY-2022 (Last updated, Version 23) |
| Name | Pyridoxal_decarbox |
| Scope(s) |
Bacteria |
| Template(s) | P05034 (DCHS_MORMO); P19113 (DCHS_HUMAN); [ Recover all ] |
| Triggered by |
HAMAP; MF_00609 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | DCHS |
| Protein name | RecName: Full=Histidine decarboxylase; Short=HDC; EC=4.1.1.22; |
| Gene name | Name=hdc; |
Comments
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| CATALYTIC ACTIVITY | Reaction=H(+) + L-histidine = CO2 + histamine; Xref=Rhea:RHEA:20840, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57595, ChEBI:CHEBI:58432; EC=4.1.1.22; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| SUBUNIT | Homotetramer. |
| SIMILARITY | Belongs to the group II decarboxylase family. |
Keywords
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Gene Ontology
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| GO:0004398; Molecular function:histidine decarboxylase activity |
Cross-references
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Features
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| From: DCHS_KLEAE (P28577) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 120 | 120 | /ligand="substrate" | H | ||||||||
| MOD_RES | 233 | 233 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
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| Size range | 369-405 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |