HAMAP rule MF_00616
General rule information
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| Accession | MF_00616 |
| Dates | 6-FEB-2003 (Created) 18-NOV-2019 (Last updated, Version 25) |
| Name | Ureidogly_lyase |
| Scope | Bacteria |
| Templates | P77731 (ALLA_ECOLI); B1XFU0 (ALLA_ECODH): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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case <OC:Escherichia> or <OC:Shigella>
| Function | Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate. |
else
| Function | Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. |
end case
| Catalytic activity | RHEA:11304: (S)-ureidoglycolate = glyoxylate + urea
EC 4.3.2.3 |
| Cofactor | Ni(2+) |
| Pathway | Nitrogen metabolism; (S)-allantoin degradation. |
| Subunit | Homodimer. |
| Similarity | Belongs to the ureidoglycolate lyase family. |
Keywords
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Gene Ontology
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GO:0050385; Molecular function: ureidoglycolate lyase activity.
GO:0000256; Biological process: allantoin catabolic process.
GO:0006145; Biological process: purine nucleobase catabolic process.
GO:0000256; Biological process: allantoin catabolic process.
GO:0006145; Biological process: purine nucleobase catabolic process.
Cross-references
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| Pfam | PF04115; Ureidogly_hydro; 1; |
| PIRSF | PIRSF017306; Ureidogly_hydro; 1; |
Additional information
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| Size range | 160-177 amino acids |
| Related rules | None |
| Fusion | None |