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HAMAP rule MF_00621

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General rule information [?]

Accession MF_00621
Dates 27-FEB-2003 (Created)
1-JUN-2023 (Last updated, Version 29)
Name HTH_type_CodY
Scope(s) Bacteria
Template(s) P39779 (CODY_BACSU); A2RHP2 (CODY_LACLM); Q81WK7 (CODY_BACAN); Q04JG7 (CODY_STRP2); Q2FZ27 (CODY_STAA8); A7X1N2 (CODY_STAA1); [ Recover all ]
Triggered by HAMAP; MF_00621 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CODY
Protein name RecName: Full=Global transcriptional regulator CodY;
Gene name Name=codY;

Comments [?]

FUNCTIONDNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
SIMILARITYBelongs to the CodY family.

Keywords [?]

Gene Ontology [?]

GO:0045892; Biological process:negative regulation of DNA-templated transcription
GO:0003677; Molecular function:DNA binding
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF06018; CodY; 1;
Pfam PF08222; HTH_CodY; 1;
NCBIfam TIGR02787; CodY_Gpos; 1;
PIRSF PIRSF011572; GTP_sensing_CodY; 1;

Features [?]

From: CODY_BACSU (P39779)
Key From To Description Tag Condition FTGroup
DNA_BIND 203 222 /note="H-T-H motif"
REGION Nter 155 /note="GAF domain"
case <OC:Bacillaceae>
MOD_RES 215 215 /note="Phosphoserine" phospho S
end case

Additional information [?]

Size range 220-300 amino acids
Related rules None
Fusion Nter: None Cter: None

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