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HAMAP rule MF_00621

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General rule information [?]

Accession MF_00621
Dates 27-FEB-2003 (Created)
1-JUN-2023 (Last updated, Version 29)
Name HTH_type_CodY
Templates P39779 (CODY_BACSU); A2RHP2 (CODY_LACLM); Q81WK7 (CODY_BACAN); Q04JG7 (CODY_STRP2); Q2FZ27 (CODY_STAA8); A7X1N2 (CODY_STAA1): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Global transcriptional regulator CodY;
Gene name

Comments [?]

Function DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
Subcellular location Cytoplasm.
Similarity Belongs to the CodY family.

Keywords [?]

case <FTTag:phospho>
end case

Gene Ontology [?]

GO:0045892; Biological process: negative regulation of DNA-templated transcription.
GO:0003677; Molecular function: DNA binding.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF06018; CodY; 1;
PF08222; HTH_CodY; 1;
NCBIfam TIGR02787; CodY_Gpos; 1;
PIRSF PIRSF011572; GTP_sensing_CodY; 1;

Features [?]

From: CODY_BACSU (P39779)
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     203     222       H-T-H motif        
REGION     Nter     155       GAF domain        
case <OC:Bacillaceae>
MOD_RES     215     215       Phosphoserine   phospho   S  
end case

Additional information [?]

Size range 220-300 amino acids
Related rules None
Fusion None