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HAMAP rule MF_00628

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General rule information [?]

Accession MF_00628
Dates 24-MAR-2003 (Created)
1-JUN-2023 (Last updated, Version 21)
Name Pept_tRNA_hydro_arch
Scope(s) Archaea
Template(s) Q60363 (PTH_METJA); Q980V1 (PTH_SACS2); [ Recover all ]
Triggered by HAMAP; MF_00628 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PTH
Protein name RecName: Full=Peptidyl-tRNA hydrolase;
Gene name Name=pth;

Comments [?]

FUNCTIONThe natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
CATALYTIC ACTIVITY Reaction=an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L- amino acid + H(+); Xref=Rhea:RHEA:54448, Rhea:RHEA-COMP:10123, Rhea:RHEA-COMP:13883, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:59874, ChEBI:CHEBI:78442, ChEBI:CHEBI:138191; EC=;
SIMILARITYBelongs to the PTH2 family.

Keywords [?]

Gene Ontology [?]

GO:0004045; Molecular function:aminoacyl-tRNA hydrolase activity
GO:0006412; Biological process:translation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01981; PTH2; 1;
NCBIfam TIGR00283; Arch_pth2; 1;

Features [?]

Additional information [?]

Size range 112-124 amino acids
Related rules None
Fusion Nter: None Cter: None

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