HAMAP rule MF_00647

General rule information [?]

Accession	MF_00647
Dates	4-JUN-2003 (Created) 1-JUN-2023 (Last updated, Version 28)

Name

PPAT_arch

Scope

Archaea

Template

Q9UYT0 (COAD_PYRAB)

Triggered by

HAMAP; MF_00647 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

COAD

Protein name

RecName:		Full=Phosphopantetheine adenylyltransferase;
		EC 2.7.7.3;
AltName:		Full=Dephospho-CoA pyrophosphorylase;
AltName:		Full=Pantetheine-phosphate adenylyltransferase;
		Short=PPAT;

Gene name

coaD

Comments [?]

Function	Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
Catalytic activity	RHEA:19801: (R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate EC 2.7.7.3
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis.
Subcellular location	Cytoplasm.
Similarity	Belongs to the eukaryotic CoaD family.

Keywords [?]

ATP-binding
Coenzyme A biosynthesis
Cytoplasm
Nucleotide-binding
Nucleotidyltransferase
Transferase

Gene Ontology [?]

GO:0004595; Molecular function: pantetheine-phosphate adenylyltransferase activity.
GO:0015937; Biological process: coenzyme A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF01467; CTP_transf_2; 1;
NCBIfam	TIGR00125; Cyt_tran_rel; 1;

Additional information [?]

Size range	147-165 amino acids
Related rules	None
Fusion	Nter: None; Cter: MF_00648 (yjjX)

View rule in raw text format (no links)