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Annotation rule MF_00647
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General rule information [?]

Accession MF_00647
Dates 4-JUN-2003 (Created)
18-NOV-2019 (Last updated, Version 26)
Name PPAT_arch
Scope
Archaea
Template Q9UYT0 (COAD_PYRAB)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
COAD
Protein name
RecName: Full=Phosphopantetheine adenylyltransferase;
EC 2.7.7.3;
AltName: Full=Dephospho-CoA pyrophosphorylase;
AltName: Full=Pantetheine-phosphate adenylyltransferase;
Short=PPAT;
Gene name
coaD

Comments [?]

Function Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
Catalytic activity RHEA:19801: ATP + D-pantetheine 4'-phosphate + H(+) = 3'-dephospho-CoA + diphosphate
EC 2.7.7.3
Pathway Cofactor biosynthesis; coenzyme A biosynthesis.
Subcellular location Cytoplasm.
Similarity Belongs to the eukaryotic CoaD family.

Keywords [?]

ATP-binding
Coenzyme A biosynthesis
Cytoplasm
Nucleotide-binding
Nucleotidyltransferase
Transferase

Gene Ontology [?]

GO:0004595; Molecular function: pantetheine-phosphate adenylyltransferase activity.
GO:0015937; Biological process: coenzyme A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
TIGRFAMs TIGR00125; Cyt_tran_rel; 1;

Additional information [?]

Size range 147-165 amino acids
Related rules None
Fusion Nter: None; Cter: MF_00648 (yjjX)


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