HAMAP rule MF_00647

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00647
Accession	MF_00647
Dates	28-FEB-2005 (Created) 01-JUN-2023 (Last updated, Version 26)
Name	PPAT_arch
Scope(s)	Archaea
Template(s)	Q9UYT0; [ Recover all ]
Triggered by	HAMAP; MF_00647 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	COAD
Protein name	RecName: Full=Phosphopantetheine adenylyltransferase; EC=2.7.7.3; AltName: Full=Dephospho-CoA pyrophosphorylase; AltName: Full=Pantetheine-phosphate adenylyltransferase; Short=PPAT;
Gene name	Name=coaD;

Comments [?]

FUNCTION	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
CATALYTIC ACTIVITY	Reaction=(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate; Xref=Rhea:RHEA:19801, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57328, ChEBI:CHEBI:61723; EC=2.7.7.3;
PATHWAY	Cofactor biosynthesis; coenzyme A biosynthesis.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the eukaryotic CoaD family.

Keywords [?]

Gene Ontology [?]

GO:0004595; Molecular function:pantetheine-phosphate adenylyltransferase activity

GO:0015937; Biological process:coenzyme A biosynthetic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF01467; CTP_transf_2; 1;
NCBIfam	TIGR00125; Cyt_tran_rel; 1;

Features [?]

Additional information [?]