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HAMAP rule MF_00647

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General rule information [?]

Accession MF_00647
Dates 4-JUN-2003 (Created)
1-JUN-2023 (Last updated, Version 28)
Name PPAT_arch
Scope(s) Archaea
Template(s) Q9UYT0 (COAD_PYRAB); [ Recover all ]
Triggered by HAMAP; MF_00647 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier COAD
Protein name RecName: Full=Phosphopantetheine adenylyltransferase;
AltName: Full=Dephospho-CoA pyrophosphorylase;
AltName: Full=Pantetheine-phosphate adenylyltransferase;
Gene name Name=coaD;

Comments [?]

FUNCTIONReversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
CATALYTIC ACTIVITY Reaction=(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate; Xref=Rhea:RHEA:19801, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57328, ChEBI:CHEBI:61723; EC=;
PATHWAYCofactor biosynthesis; coenzyme A biosynthesis.
SIMILARITYBelongs to the eukaryotic CoaD family.

Keywords [?]

Gene Ontology [?]

GO:0004595; Molecular function:pantetheine-phosphate adenylyltransferase activity
GO:0015937; Biological process:coenzyme A biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
NCBIfam TIGR00125; Cyt_tran_rel; 1;

Features [?]

Additional information [?]

Size range 147-165 amino acids
Related rules None
Fusion Nter: None Cter: MF_00648 (yjjX)

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