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HAMAP rule MF_00654

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General rule information [?]

Accession MF_00654
Dates 13-JUN-2003 (Created)
1-JUN-2023 (Last updated, Version 27)
Name PQQ_syn_PqqC
Scope(s) Bacteria
Template(s) P27505 (PQQC_KLEPN); [ Recover all ]
Triggered by HAMAP; MF_00654 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PQQC
Protein name RecName: Full=Pyrroloquinoline-quinone synthase;
AltName: Full=Coenzyme PQQ synthesis protein C;
AltName: Full=Pyrroloquinoline quinone biosynthesis protein C;
Gene name Name=pqqC;

Comments [?]

FUNCTIONRing cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
CATALYTIC ACTIVITY Reaction=6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8- hexahydroquinoline-2,4-dicarboxylate + 3 O2 = H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone; Xref=Rhea:RHEA:10692, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:58442, ChEBI:CHEBI:58778; EC=;
PATHWAYCofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
SIMILARITYBelongs to the PqqC family.

Keywords [?]

Gene Ontology [?]

GO:0018189; Biological process:pyrroloquinoline quinone biosynthetic process

Cross-references [?]

Pfam PF03070; TENA_THI-4; 1;
NCBIfam TIGR02111; PQQ_syn_pqqC; 1;

Features [?]

Additional information [?]

Size range 239-268 amino acids
Related rules None
Fusion Nter: None Cter: MF_00655 (pqqD)

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