HAMAP rule MF_00654

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00654
Accession	MF_00654
Dates	28-FEB-2005 (Created) 02-SEP-2024 (Last updated, Version 24)
Name	PQQ_syn_PqqC
Scope(s)	Bacteria
Template(s)	P27505; [ Recover all ]
Triggered by	HAMAP; MF_00654 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PQQC
Protein name	RecName: Full=Pyrroloquinoline-quinone synthase; EC=1.3.3.11; AltName: Full=Coenzyme PQQ synthesis protein C; AltName: Full=Pyrroloquinoline quinone biosynthesis protein C;
Gene name	Name=pqqC;

Comments [?]

FUNCTION	Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
CATALYTIC ACTIVITY	Reaction=6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8- hexahydroquinoline-2,4-dicarboxylate + 3 O2 = pyrroloquinoline quinone + 2 H2O2 + 2 H2O + H(+); Xref=Rhea:RHEA:10692, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:58442, ChEBI:CHEBI:58778; EC=1.3.3.11;
PATHWAY	Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
SIMILARITY	Belongs to the PqqC family.

Keywords [?]

Gene Ontology [?]

GO:0018189; Biological process:pyrroloquinoline quinone biosynthetic process

Cross-references [?]

Pfam	PF03070; TENA_THI-4; 1;
NCBIfam	TIGR02111; PQQ_syn_pqqC; 1;

Features [?]

Additional information [?]