Home  |  Contact
Annotation rule MF_00668
Send feedback

General rule information [?]

Accession MF_00668
Dates 7-JUL-2003 (Created)
21-JAN-2020 (Last updated, Version 25)
Name BioW
Scope
Bacteria
Archaea
Template P22822 (BIOW_LYSSH)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
BIOW
Protein name
RecName: Full=6-carboxyhexanoate--CoA ligase;
EC 6.2.1.14;
AltName: Full=Pimeloyl-CoA synthase;
Gene name
bioW

Comments [?]

Function Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
Catalytic activity RHEA:14781: ATP + CoA + heptanedioate = 6-carboxyhexanoyl-CoA + AMP + diphosphate
EC 6.2.1.14
Cofactor Mg(2+)
Pathway Metabolic intermediate metabolism; pimeloyl-CoA biosynthesis; pimeloyl-CoA from pimelate: step 1/1.
Subunit Homodimer.
Similarity Belongs to the BioW family.

Keywords [?]


Gene Ontology [?]

GO:0042410; Molecular function: 6-carboxyhexanoate-CoA ligase activity.
GO:0000287; Molecular function: magnesium ion binding.
GO:0009102; Biological process: biotin biosynthetic process.

Cross-references [?]

Pfam PF03744; BioW; 1;
TIGRFAMs TIGR01204; BioW; 1;

Additional information [?]

Size range 228-259 amino acids
Related rules None
Fusion Nter: None; Cter: MF_01693 (bioF)