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HAMAP rule MF_00668

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General rule information [?]

Accession MF_00668
Dates 7-JUL-2003 (Created)
1-JUN-2023 (Last updated, Version 26)
Name BioW
Scope(s) Bacteria
Template(s) P22822 (BIOW_LYSSH); [ Recover all ]
Triggered by HAMAP; MF_00668 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier BIOW
Protein name RecName: Full=6-carboxyhexanoate--CoA ligase;
AltName: Full=Pimeloyl-CoA synthase;
Gene name Name=bioW;

Comments [?]

FUNCTIONCatalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
CATALYTIC ACTIVITY Reaction=ATP + CoA + heptanedioate = 6-carboxyhexanoyl-CoA + AMP + diphosphate; Xref=Rhea:RHEA:14781, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:36165, ChEBI:CHEBI:57287, ChEBI:CHEBI:57360, ChEBI:CHEBI:456215; EC=;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
PATHWAYMetabolic intermediate metabolism; pimeloyl-CoA biosynthesis; pimeloyl-CoA from pimelate: step 1/1.
SIMILARITYBelongs to the BioW family.

Keywords [?]

Gene Ontology [?]

GO:0042410; Molecular function:6-carboxyhexanoate-CoA ligase activity
GO:0000287; Molecular function:magnesium ion binding
GO:0009102; Biological process:biotin biosynthetic process

Cross-references [?]

Pfam PF03744; BioW; 1;
NCBIfam TIGR01204; BioW; 1;

Features [?]

Additional information [?]

Size range 228-259 amino acids
Related rules None
Fusion Nter: None Cter: MF_01693 (bioF)

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