HAMAP rule MF_00668
General rule information
[?]
| PURL | https://purl.expasy.org/hamap/rule/MF_00668 |
| Accession | MF_00668 |
| Dates | 28-FEB-2005 (Created)
02-SEP-2024 (Last updated, Version 26) |
| Name | BioW |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P22822; [ Recover all ] |
| Triggered by |
HAMAP; MF_00668 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | BIOW |
| Protein name | RecName: Full=6-carboxyhexanoate--CoA ligase; EC=6.2.1.14; AltName: Full=Pimeloyl-CoA synthase; |
| Gene name | Name=bioW; |
Comments
[?]
| FUNCTION | Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP. |
| CATALYTIC ACTIVITY | Reaction=heptanedioate + ATP + CoA = 6-carboxyhexanoyl-CoA + AMP + diphosphate; Xref=Rhea:RHEA:14781, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:36165, ChEBI:CHEBI:57287, ChEBI:CHEBI:57360, ChEBI:CHEBI:456215; EC=6.2.1.14; |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| PATHWAY | Metabolic intermediate metabolism; pimeloyl-CoA biosynthesis; pimeloyl-CoA from pimelate: step 1/1. |
| SUBUNIT | Homodimer. |
| SIMILARITY | Belongs to the BioW family. |
Keywords
[?]
Gene Ontology
[?]
| GO:0042410; Molecular function:6-carboxyhexanoate-CoA ligase activity |
| GO:0000287; Molecular function:magnesium ion binding |
| GO:0009102; Biological process:biotin biosynthetic process |
Cross-references
[?]
Features
[?]
Additional information
[?]
| Size range | 228-259 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: MF_01693 (bioF) |