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HAMAP rule MF_00681

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General rule information [?]

Accession MF_00681
Dates 16-JUL-2003 (Created)
18-NOV-2019 (Last updated, Version 23)
Name MfnB
Scope(s) Archaea
Template(s) Q58499 (MFNB_METJA); [ Recover all ]
Triggered by HAMAP; MF_00681 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MFNB
Protein name RecName: Full=(5-formylfuran-3-yl)methyl phosphate synthase;
AltName: Full=4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase;
                 Short=4-HFC-P synthase;
Gene name Name=mfnB;

Comments [?]

FUNCTIONCatalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
CATALYTIC ACTIVITY Reaction=2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate + 2 H2O + phosphate; Xref=Rhea:RHEA:43536, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:59776, ChEBI:CHEBI:83407; EC=;
PATHWAYCofactor biosynthesis; methanofuran biosynthesis.
SIMILARITYBelongs to the MfnB family.

Keywords [?]

Gene Ontology [?]

GO:0016830; Molecular function:carbon-carbon lyase activity
GO:2001120; Biological process:methanofuran biosynthetic process

Cross-references [?]

Pfam PF04476; DUF556; 1;
PIRSF PIRSF015957; UCP015957; 1;

Features [?]

From: MFNB_METJA (Q58499)
Key From To Description Tag Condition FTGroup
ACT_SITE 27 27 /note="Schiff-base intermediate with substrate" K
ACT_SITE 85 85 /note="Proton acceptor" K

Additional information [?]

Size range 225-250 amino acids
Related rules None
Fusion Nter: None Cter: None

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