HAMAP rule MF_00681

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00681
Accession	MF_00681
Dates	28-FEB-2005 (Created) 02-SEP-2024 (Last updated, Version 21)
Name	MfnB
Scope(s)	Archaea
Template(s)	Q58499; [ Recover all ]
Triggered by	HAMAP; MF_00681 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MFNB
Protein name	RecName: Full=(5-formylfuran-3-yl)methyl phosphate synthase; EC=4.2.3.153; AltName: Full=4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase; Short=4-HFC-P synthase;
Gene name	Name=mfnB;

Comments [?]

FUNCTION	Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
CATALYTIC ACTIVITY	Reaction=2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate + phosphate + 2 H2O; Xref=Rhea:RHEA:43536, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:59776, ChEBI:CHEBI:83407; EC=4.2.3.153;
PATHWAY	Cofactor biosynthesis; methanofuran biosynthesis.
SIMILARITY	Belongs to the MfnB family.

Keywords [?]

Gene Ontology [?]

GO:0016830; Molecular function:carbon-carbon lyase activity

GO:2001120; Biological process:methanofuran biosynthetic process

Cross-references [?]

Pfam	PF04476; DUF556; 1;
PIRSF	PIRSF015957; UCP015957; 1;

Features [?]

From: MFNB_METJA (Q58499)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

/note="Schiff-base intermediate with substrate"

ACT_SITE

/note="Proton acceptor"

Additional information [?]