HAMAP logo

HAMAP rule MF_00684

Send feedback

General rule information [?]

Accession MF_00684
Dates 18-JUL-2003 (Created)
26-JAN-2023 (Last updated, Version 20)
Name ac4C_amidohydr
Scope(s) Bacteria
Template(s) P67603 (AC4CH_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00684 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier AC4CH
Protein name RecName: Full=N(4)-acetylcytidine amidohydrolase;
                 Short=ac4C amidohydrolase;

Comments [?]

FUNCTIONCatalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
CATALYTIC ACTIVITY Reaction=H2O + N(4)-acetylcytidine = acetate + cytidine + H(+); Xref=Rhea:RHEA:62932, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17562, ChEBI:CHEBI:30089, ChEBI:CHEBI:70989; EC=;
CATALYTIC ACTIVITY Reaction=H2O + N(4)-acetyl-2'-deoxycytidine = 2'-deoxycytidine + acetate + H(+); Xref=Rhea:RHEA:62936, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15698, ChEBI:CHEBI:30089, ChEBI:CHEBI:146133; EC=;
CATALYTIC ACTIVITY Reaction=H2O + N(4)-acetylcytosine = acetate + cytosine + H(+); Xref=Rhea:RHEA:62940, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16040, ChEBI:CHEBI:30089, ChEBI:CHEBI:146134; EC=;
SIMILARITYBelongs to the N(4)-acetylcytidine amidohydrolase family.

Keywords [?]

Gene Ontology [?]

GO:0016813; Molecular function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

Cross-references [?]

Pfam PF04266; ASCH; 1;
PIRSF PIRSF029143; UCP029143; 1;

Features [?]

From: AC4CH_ECOLI (P67603)
Key From To Description Tag Condition FTGroup
ACT_SITE 21 21 /note="Proton acceptor" K
ACT_SITE 24 24 /note="Nucleophile" [TS]
ACT_SITE 74 74 /note="Proton donor" E

Additional information [?]

Size range 90-160 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)