HAMAP rule MF_00684

General rule information [?]

Accession	MF_00684
Dates	18-JUL-2003 (Created) 26-JAN-2023 (Last updated, Version 20)
Name	ac4C_amidohydr
Scope(s)	Bacteria Pseudomonadota
Template(s)	P67603 (AC4CH_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00684 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	AC4CH
Protein name	RecName: Full=N(4)-acetylcytidine amidohydrolase; Short=ac4C amidohydrolase; EC=3.5.1.135;

Comments [?]

FUNCTION	Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
CATALYTIC ACTIVITY	Reaction=H2O + N(4)-acetylcytidine = acetate + cytidine + H(+); Xref=Rhea:RHEA:62932, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17562, ChEBI:CHEBI:30089, ChEBI:CHEBI:70989; EC=3.5.1.135;
CATALYTIC ACTIVITY	Reaction=H2O + N(4)-acetyl-2'-deoxycytidine = 2'-deoxycytidine + acetate + H(+); Xref=Rhea:RHEA:62936, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15698, ChEBI:CHEBI:30089, ChEBI:CHEBI:146133; EC=3.5.1.135;
CATALYTIC ACTIVITY	Reaction=H2O + N(4)-acetylcytosine = acetate + cytosine + H(+); Xref=Rhea:RHEA:62940, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16040, ChEBI:CHEBI:30089, ChEBI:CHEBI:146134; EC=3.5.1.135;
SIMILARITY	Belongs to the N(4)-acetylcytidine amidohydrolase family.

Keywords [?]

Gene Ontology [?]

GO:0016813; Molecular function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines

Cross-references [?]

Pfam	PF04266; ASCH; 1;
PIRSF	PIRSF029143; UCP029143; 1;

Features [?]

From: AC4CH_ECOLI (P67603)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

/note="Proton acceptor"

ACT_SITE

/note="Nucleophile"

[TS]

ACT_SITE

/note="Proton donor"

Additional information [?]