HAMAP rule MF_00684
General rule information
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Accession | MF_00684 |
Dates | 18-JUL-2003 (Created) 26-JAN-2023 (Last updated, Version 20) |
Name | ac4C_amidohydr |
Scope | Bacteria; Pseudomonadota |
Template | P67603 (AC4CH_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Comments
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Function | Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C). |
Catalytic activity | RHEA:62932: H2O + N(4)-acetylcytidine = acetate + cytidine + H(+)
EC 3.5.1.135 |
RHEA:62936: H2O + N(4)-acetyl-2'-deoxycytidine = 2'-deoxycytidine + acetate + H(+)
EC 3.5.1.135 |
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RHEA:62940: H2O + N(4)-acetylcytosine = acetate + cytosine + H(+)
EC 3.5.1.135 |
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Similarity | Belongs to the N(4)-acetylcytidine amidohydrolase family. |
Keywords
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Gene Ontology
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GO:0016813; Molecular function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines.
Cross-references
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Pfam | PF04266; ASCH; 1; |
PIRSF | PIRSF029143; UCP029143; 1; |
Features
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From: AC4CH_ECOLI (P67603) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 21 | 21 | Proton acceptor | K | ||||||||
ACT_SITE | 24 | 24 | Nucleophile | [TS] | ||||||||
ACT_SITE | 74 | 74 | Proton donor | E |
Additional information
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Size range | 90-160 amino acids |
Related rules | None |
Fusion | None |