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HAMAP rule MF_00685

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General rule information [?]

Accession MF_00685
Dates 18-AUG-2003 (Created)
28-NOV-2023 (Last updated, Version 31)
Name GlgB
Scope(s) Bacteria
Template(s) P07762 (GLGB_ECOLI); P9WN45 (GLGB_MYCTU); Q8GQC5 (GLGB_DICCH); [ Recover all ]
Triggered by HAMAP; MF_00685 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GLGB
Protein name RecName: Full=1,4-alpha-glucan branching enzyme GlgB;
AltName: Full=1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase;
AltName: Full=Alpha-(1->4)-glucan branching enzyme;
AltName: Full=Glycogen branching enzyme;
Gene name Name=glgB;

Comments [?]

FUNCTIONCatalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
CATALYTIC ACTIVITY Reaction=Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.; EC=;
PATHWAYGlycan biosynthesis; glycogen biosynthesis.
SIMILARITYBelongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0003844; Molecular function:1,4-alpha-glucan branching enzyme activity
GO:0005978; Biological process:glycogen biosynthetic process

Cross-references [?]

Pfam PF00128; Alpha-amylase; 1;
Pfam PF02806; Alpha-amylase_C; 1;
Pfam PF02922; CBM_48; 1;
NCBIfam TIGR01515; branching_enzym; 1;

Features [?]

Key From To Description Tag Condition FTGroup
ACT_SITE 411 411 /note="Nucleophile" D
ACT_SITE 464 464 /note="Proton donor" E

Additional information [?]

Size range 611-838 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments GlgB from M.tuberculosis is involved in the biosynthesis of both glycogen and capsular alpha-D-glucan.

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