HAMAP rule MF_00685
General rule information
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| Accession | MF_00685 |
| Dates | 18-AUG-2003 (Created)
1-JUN-2023 (Last updated, Version 29) |
| Name | GlgB |
| Scope(s) |
Bacteria Archaea Thermoplasmata |
| Template(s) | P07762 (GLGB_ECOLI); P9WN45 (GLGB_MYCTU); Q8GQC5 (GLGB_DICCH); [ Recover all ] |
| Triggered by |
HAMAP; MF_00685 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | GLGB |
| Protein name | RecName: Full=1,4-alpha-glucan branching enzyme GlgB; EC=2.4.1.18; AltName: Full=1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase; AltName: Full=Alpha-(1->4)-glucan branching enzyme; AltName: Full=Glycogen branching enzyme; Short=BE; |
| Gene name | Name=glgB; |
Comments
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| FUNCTION | Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. |
| CATALYTIC ACTIVITY | Reaction=Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.; EC=2.4.1.18; |
| PATHWAY | Glycan biosynthesis; glycogen biosynthesis. |
| SUBUNIT | Monomer. |
| SIMILARITY | Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. |
Keywords
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Gene Ontology
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| GO:0003844; Molecular function:1,4-alpha-glucan branching enzyme activity |
| GO:0005978; Biological process:glycogen biosynthetic process |
Cross-references
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| Pfam | PF00128; Alpha-amylase; 1; |
| Pfam | PF02806; Alpha-amylase_C; 1; |
| Pfam | PF02922; CBM_48; 1; |
| NCBIfam | TIGR01515; branching_enzym; 1; |
Features
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| From: GLGB_MYCTU (P9WN45) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 411 | 411 | /note="Nucleophile" | D | ||||||||
| ACT_SITE | 464 | 464 | /note="Proton donor" | E | ||||||||
Additional information
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| Size range | 611-838 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | GlgB from M.tuberculosis is involved in the biosynthesis of both glycogen and capsular alpha-D-glucan. |