HAMAP rule MF_00691

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00691
Accession	MF_00691
Dates	28-FEB-2005 (Created) 02-SEP-2024 (Last updated, Version 26)
Name	PxpA
Scope(s)	Bacteria Archaea Thermococcales
Template(s)	P42963; P75746; [ Recover all ]
Triggered by	HAMAP; MF_00691 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PXPA
Protein name	RecName: Full=5-oxoprolinase subunit A; Short=5-OPase subunit A; EC=3.5.2.9; AltName: Full=5-oxoprolinase (ATP-hydrolyzing) subunit A;
Gene name	Name=pxpA;

Comments [?]

FUNCTION	Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
CATALYTIC ACTIVITY	Reaction=5-oxo-L-proline + ATP + 2 H2O = L-glutamate + ADP + phosphate + H(+); Xref=Rhea:RHEA:10348, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58402, ChEBI:CHEBI:456216; EC=3.5.2.9;
SUBUNIT	Forms a complex composed of PxpA, PxpB and PxpC.
SIMILARITY	Belongs to the LamB/PxpA family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0017168; Molecular function:5-oxoprolinase (ATP-hydrolyzing) activity

Cross-references [?]

Pfam	PF03746; LamB_YcsF; 1;

Features [?]

Additional information [?]