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HAMAP rule MF_00691

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General rule information [?]

Accession MF_00691
Dates 29-JUL-2003 (Created)
28-NOV-2023 (Last updated, Version 30)
Name PxpA
Scope(s) Bacteria
Archaea
Thermococcales
Template(s) P42963 (PXPA_BACSU); P75746 (PXPA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00691 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PXPA
Protein name RecName: Full=5-oxoprolinase subunit A;
                 Short=5-OPase subunit A;
                 EC=3.5.2.9;
AltName: Full=5-oxoprolinase (ATP-hydrolyzing) subunit A;
Gene name Name=pxpA;

Comments [?]

FUNCTIONCatalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
CATALYTIC ACTIVITY Reaction=5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate + phosphate; Xref=Rhea:RHEA:10348, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58402, ChEBI:CHEBI:456216; EC=3.5.2.9;
SUBUNITForms a complex composed of PxpA, PxpB and PxpC.
SIMILARITYBelongs to the LamB/PxpA family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0017168; Molecular function:5-oxoprolinase (ATP-hydrolyzing) activity

Cross-references [?]

Pfam PF03746; LamB_YcsF; 1;

Features [?]


Additional information [?]

Size range 230-310 amino acids
Related rules None
Fusion Nter: None Cter: None



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