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HAMAP rule MF_00692

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General rule information [?]

Accession MF_00692
Dates 29-JUL-2003 (Created)
19-NOV-2022 (Last updated, Version 26)
Name SelO
Scope
Bacteria
Templates Q87VB1 (SELO_PSESM); P77649 (SELO_ECOLI): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SELO
Protein name
RecName: Full=Protein adenylyltransferase SelO;
EC 2.7.7.108;
Gene name
selO

Comments [?]

Function Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
Catalytic activity RHEA:54288: ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]
EC 2.7.7.108
PhysiologicalDirection=left-to-right (RHEA:54289)
RHEA:54292: ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate
EC 2.7.7.108
PhysiologicalDirection=left-to-right (RHEA:54293)
RHEA:58120: ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate
EC 2.7.7.108
PhysiologicalDirection=left-to-right (RHEA:58121)
Cofactor Mg(2+)
Similarity Belongs to the SELO family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0016779; Molecular function: nucleotidyltransferase activity.

Cross-references [?]

Pfam PF02696; UPF0061; 1;

Features [?]

From: SELO_PSESM (Q87VB1)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     90     93       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-D-G-R  
BINDING     125     126       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     D-G  
ACT_SITE     252     252       Proton acceptor     D  
BINDING     253     253       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     N  
BINDING     262     262       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420     D  
BINDING     113     113       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     K  
BINDING     176     176       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     R  
BINDING     183     183       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     R  

Additional information [?]

Size range 450-650 amino acids
Related rules None
Fusion None