HAMAP rule MF_00698
General rule information
[?]
| PURL | https://purl.expasy.org/hamap/rule/MF_00698 |
| Accession | MF_00698 |
| Dates | 28-FEB-2005 (Created)
18-NOV-2019 (Last updated, Version 14) |
| Name | Aminopeptidase_S15 |
| Scope(s) |
Bacteria Lactobacillales |
| Template(s) | P22346; Q93M42; [ Recover all ] |
| Triggered by |
HAMAP; MF_00698 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | PEPX |
| Protein name | RecName: Full=Xaa-Pro dipeptidyl-peptidase; EC=3.4.14.11; AltName: Full=X-Pro dipeptidyl-peptidase; AltName: Full=X-prolyl-dipeptidyl aminopeptidase; Short=X-PDAP; |
| Gene name | Name=pepX; |
Comments
[?]
| FUNCTION | Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. |
| CATALYTIC ACTIVITY | Reaction=Hydrolyzes Xaa-Pro-|- bonds to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-|-p-nitroanilide and (sequentially) Tyr-Pro-|-Phe-Pro-|-Gly-Pro-|-Ile.; EC=3.4.14.11; |
| SUBUNIT | Homodimer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the peptidase S15 family. |
Keywords
[?]
Gene Ontology
[?]
| GO:0008239; Molecular function:dipeptidyl-peptidase activity |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
Features
[?]
| From: PEPX_LACLC (P22346) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 348 | 348 | /note="Charge relay system" | S | ||||||||
| ACT_SITE | 468 | 468 | /note="Charge relay system" | D | ||||||||
| ACT_SITE | 498 | 498 | /note="Charge relay system" | H | ||||||||
Additional information
[?]
| Size range | 755-813 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |