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Annotation rule MF_00698
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General rule information [?]

Accession MF_00698
Dates 22-AUG-2003 (Created)
18-NOV-2019 (Last updated, Version 18)
Name Aminopeptidase_S15
Scope
Bacteria; Lactobacillales
Templates P22346 (PEPX_LACLC); Q93M42 (PEPX_STRGN): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PEPX
Protein name
RecName: Full=Xaa-Pro dipeptidyl-peptidase;
EC 3.4.14.11;
AltName: Full=X-Pro dipeptidyl-peptidase;
AltName: Full=X-prolyl-dipeptidyl aminopeptidase;
Short=X-PDAP;
Gene name
pepX

Comments [?]

Function Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Catalytic activity Reaction=Hydrolyzes Xaa-Pro-|- bonds to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-|-p-nitroanilide and (sequentially) Tyr-Pro-|-Phe-Pro-|-Gly-Pro-|-Ile.; EC=3.4.14.11;
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the peptidase S15 family.

Keywords [?]

Cytoplasm
Hydrolase
Protease
Serine protease
Aminopeptidase

Gene Ontology [?]

GO:0008239; Molecular function: dipeptidyl-peptidase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02129; Peptidase_S15; 1;
PRINTS PR00923; LACTOPTASE; 1;

Features [?]

From: PEPX_LACLC (P22346)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     348     348       Charge relay system     S  
ACT_SITE     468     468       Charge relay system     D  
ACT_SITE     498     498       Charge relay system     H  

Additional information [?]

Size range 755-813 amino acids
Related rules None
Fusion None


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