HAMAP rule MF_00698

General rule information [?]

Accession	MF_00698
Dates	22-AUG-2003 (Created) 18-NOV-2019 (Last updated, Version 18)

Name	Aminopeptidase_S15

Scope

Bacteria; Lactobacillales

Templates

P22346 (PEPX_LACLC); Q93M42 (PEPX_STRGN): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

PEPX

Protein name

RecName:		Full=Xaa-Pro dipeptidyl-peptidase;
		EC 3.4.14.11;
AltName:		Full=X-Pro dipeptidyl-peptidase;
AltName:		Full=X-prolyl-dipeptidyl aminopeptidase;
		Short=X-PDAP;

Gene name

pepX

Comments [?]

Function	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Catalytic activity	Reaction=Hydrolyzes Xaa-Pro-\|- bonds to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-\|-p-nitroanilide and (sequentially) Tyr-Pro-\|-Phe-Pro-\|-Gly-Pro-\|-Ile.; EC=3.4.14.11;
Subunit	Homodimer.
Subcellular location	Cytoplasm.
Similarity	Belongs to the peptidase S15 family.

Keywords [?]

Gene Ontology [?]

GO:0008239; Molecular function: dipeptidyl-peptidase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF02129; Peptidase_S15; 1;
PRINTS	PR00923; LACTOPTASE; 1;

Features [?]

From: PEPX_LACLC (P22346)

Key From To Description Tag Condition FTGroup

ACT_SITE 348 348 Charge relay system S

ACT_SITE 468 468 Charge relay system D

ACT_SITE 498 498 Charge relay system H

Additional information [?]