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Annotation rule MF_00704
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General rule information [?]

Accession MF_00704
Dates 27-AUG-2003 (Created)
19-NOV-2022 (Last updated, Version 20)
Name Aspartoacylase
Scope
Bacteria; Cyanobacteria
Template P45381 (ACY2_HUMAN)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ASPA
Protein name
RecName: Full=Probable aspartoacylase;
EC 3.5.1.15;

Comments [?]

Catalytic activity RHEA:10872: H2O + N-acyl-L-aspartate = a carboxylate + L-aspartate
EC 3.5.1.15
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
Similarity Belongs to the AspA/AstE family. Aspartoacylase subfamily.

Keywords [?]

Hydrolase
case <FTGroup:1>
Metal-binding
Zinc
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0019807; Molecular function: aspartoacylase activity.

Cross-references [?]

Pfam PF04952; AstE_AspA; 1;
PIRSF PIRSF018001; Aspartoacylase; 1;

Features [?]

From: ASPA_NOSS1 (Q8YQC1)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     63     64       /ligand="substrate     N-R  
BINDING     14     14       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     H   1
BINDING     17     17       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     E   1
BINDING     106     106       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     H   1
BINDING     56     56       /ligand="substrate     R  
BINDING     164     164       /ligand="substrate     E  
BINDING     275     275       /ligand="substrate     Y  

Additional information [?]

Size range 288-307 amino acids
Related rules None
Fusion None


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