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HAMAP rule MF_00706

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General rule information [?]

Accession MF_00706
Dates 1-SEP-2003 (Created)
18-NOV-2019 (Last updated, Version 25)
Name Ecotin
Scope(s) Bacteria
Template(s) P23827 (ECOT_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00706 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ECOT
Protein name RecName: Full=Ecotin;
                 Flags: Precursor;
Gene name Name=eco;

Comments [?]

case <OC:Enterobacterales>
FUNCTIONGeneral inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
FUNCTIONGeneral inhibitor of family S1 serine proteases.
end case
SIMILARITYBelongs to the protease inhibitor I11 (ecotin) family.

Keywords [?]

Gene Ontology [?]

GO:0004867; Molecular function:serine-type endopeptidase inhibitor activity
GO:0042597; Cellular component:periplasmic space

Cross-references [?]

Pfam PF03974; Ecotin; 1;
General Signal; -; 1;

Features [?]

From: ECOT_ECOLI (P23827)
Key From To Description Tag Condition FTGroup
SITE 104 105 /note="Reactive bond" x-M
DISULFID 70 107 C-x*-C

Additional information [?]

Size range 156-183 amino acids
Related rules None
Fusion Nter: None Cter: None

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