HAMAP rule MF_00706
General rule information
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Accession | MF_00706 |
Dates | 1-SEP-2003 (Created) 18-NOV-2019 (Last updated, Version 25) |
Name | Ecotin |
Scope | Bacteria |
Template | P23827 (ECOT_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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case <OC:Enterobacterales>
Function | General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. |
else
Function | General inhibitor of family S1 serine proteases. |
end case
Subunit | Homodimer. |
Subcellular location | Periplasm. |
Similarity | Belongs to the protease inhibitor I11 (ecotin) family. |
Keywords
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case <FT:2>
end case
Gene Ontology
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GO:0004867; Molecular function: serine-type endopeptidase inhibitor activity.
GO:0042597; Cellular component: periplasmic space.
GO:0042597; Cellular component: periplasmic space.
Cross-references
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Pfam | PF03974; Ecotin; 1; |
Computed features
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General | Signal; -; 1; trigger=yes; |
Features
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From: ECOT_ECOLI (P23827) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
SITE | 104 | 105 | Reactive bond | x-M | ||||||||
DISULFID | 70 | 107 | C-x*-C |
Additional information
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Size range | 156-183 amino acids |
Related rules | None |
Fusion | None |