HAMAP rule MF_00714
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00714 |
| Accession | MF_00714 |
| Dates | 28-FEB-2005 (Created)
18-NOV-2019 (Last updated, Version 15) |
| Name | MerB |
| Scope(s) |
Bacteria |
| Template(s) | P08653; [ Recover all ] |
| Triggered by |
HAMAP; MF_00714 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MERB |
| Protein name | RecName: Full=Alkylmercury lyase; EC=4.99.1.2; AltName: Full=Organomercurial lyase; |
| Gene name | Name=merB; |
Comments
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| FUNCTION | Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase. |
| CATALYTIC ACTIVITY | Reaction=an alkylmercury + H(+) = an alkane + Hg(2+); Xref=Rhea:RHEA:18777, ChEBI:CHEBI:15378, ChEBI:CHEBI:16793, ChEBI:CHEBI:18310, ChEBI:CHEBI:83725; EC=4.99.1.2; |
| SIMILARITY | Belongs to the MerB family. |
Keywords
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Gene Ontology
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| GO:0046689; Biological process:response to mercury ion |
| GO:0018836; Molecular function:alkylmercury lyase activity |
Cross-references
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Features
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Additional information
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| Size range | 212-218 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |