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| Annotation rule MF_00728 |
General rule information
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| Accession | MF_00728 |
| Dates | 17-NOV-2003 (Created) 18-NOV-2019 (Last updated, Version 24) |
| Name | EzrA |
| Scope | Bacteria; Firmicutes |
| Template | O34894 (EZRA_BACSU) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization. |
| Subcellular location | Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site. |
| Similarity | Belongs to the EzrA family. |
Keywords
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Cell cycle
Cell division
Cell membrane
Septation
Membrane
Transmembrane
Coiled coil
Transmembrane helix
Cell division
Cell membrane
Septation
Membrane
Transmembrane
Coiled coil
Transmembrane helix
Gene Ontology
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GO:0090529; Biological process: cell septum assembly.
GO:0005886; Cellular component: plasma membrane.
GO:0005886; Cellular component: plasma membrane.
Computed features
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| General | Coiled_coil; -; 1-unlimited; trigger=yes; |
Features
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| From: EZRA_BACSU (O34894) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 2 | Extracellular | |||||||||
| TRANSMEM | 3 | 21 | Helical | |||||||||
| TOPO_DOM | 22 | Cter | Cytoplasmic | |||||||||
Additional information
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| Size range | 561-578 amino acids |
| Related rules | None |
| Fusion | None |