HAMAP rule MF_00728
General rule information
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Accession | MF_00728 |
Dates | 17-NOV-2003 (Created)
13-JAN-2023 (Last updated, Version 25) |
Name | EzrA |
Scope(s) |
Bacteria Bacillota |
Template(s) | O34894 (EZRA_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_00728 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | EZRA |
Protein name | RecName: Full=Septation ring formation regulator EzrA; |
Gene name | Name=ezrA; |
Comments
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FUNCTION | Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization. |
SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site. |
SIMILARITY | Belongs to the EzrA family. |
Keywords
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Cell cycle |
Cell division |
Cell membrane |
Septation |
Membrane |
Transmembrane |
Coiled coil |
Transmembrane helix |
Gene Ontology
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GO:0090529; Biological process:cell septum assembly |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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General | Coiled_coil; -; 1-unlimited; |
Features
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From: EZRA_BACSU (O34894) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 2 | /note="Extracellular" | |||||||||
TRANSMEM | 3 | 21 | /note="Helical" | |||||||||
TOPO_DOM | 22 | Cter | /note="Cytoplasmic" |
Additional information
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Size range | 561-578 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |