HAMAP rule MF_00728
General rule information
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| Accession | MF_00728 |
| Dates | 17-NOV-2003 (Created)
13-JAN-2023 (Last updated, Version 25) |
| Name | EzrA |
| Scope(s) |
Bacteria Bacillota |
| Template(s) | O34894 (EZRA_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00728 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | EZRA |
| Protein name | RecName: Full=Septation ring formation regulator EzrA; |
| Gene name | Name=ezrA; |
Comments
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| FUNCTION | Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization. |
| SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site. |
| SIMILARITY | Belongs to the EzrA family. |
Keywords
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| Cell cycle |
| Cell division |
| Cell membrane |
| Septation |
| Membrane |
| Transmembrane |
| Coiled coil |
| Transmembrane helix |
Gene Ontology
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| GO:0090529; Biological process:cell septum assembly |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| General | Coiled_coil; -; 1-unlimited; |
Features
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| From: EZRA_BACSU (O34894) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 2 | /note="Extracellular" | |||||||||
| TRANSMEM | 3 | 21 | /note="Helical" | |||||||||
| TOPO_DOM | 22 | Cter | /note="Cytoplasmic" | |||||||||
Additional information
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| Size range | 561-578 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |