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HAMAP rule MF_00732
General rule information
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| Accession | MF_00732 |
| Dates | 21-NOV-2003 (Created)
7-FEB-2023 (Last updated, Version 29) |
| Name | HTH_MntR |
| Scope(s) |
Bacteria Bacilli |
| Template(s) | P54512 (MNTR_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00732 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MNTR |
| Protein name | RecName: Full=HTH-type transcriptional regulator MntR; AltName: Full=Manganese transport regulator; |
| Gene name | Name=mntR; |
Comments
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| FUNCTION | Central regulator of manganese homeostasis. |
| ACTIVITY REGULATION | DNA binding is strongly activated by Mn(2+). |
| SUBUNIT | Homodimer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the DtxR/MntR family. |
Keywords
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| Activator |
| Cytoplasm |
| DNA-binding |
| Manganese |
| Metal-binding |
| Repressor |
| Transcription |
| Transcription regulation |
Gene Ontology
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| GO:0030145; Molecular function:manganese ion binding |
| GO:0003700; Molecular function:DNA-binding transcription factor activity |
| GO:0030026; Biological process:intracellular manganese ion homeostasis |
| GO:0006355; Biological process:regulation of DNA-templated transcription |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: MNTR_BACSU (P54512) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 8 | 8 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1" |
D | ||||||||
| BINDING | 11 | 11 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2" |
E | ||||||||
| BINDING | 77 | 77 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2" |
H | ||||||||
| BINDING | 99 | 99 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1" |
E | ||||||||
| BINDING | 99 | 99 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2" |
E | ||||||||
| BINDING | 102 | 102 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1" |
E | ||||||||
| BINDING | 102 | 102 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2" |
E | ||||||||
| BINDING | 103 | 103 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1" |
H | ||||||||
Additional information
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| Size range | 130-170 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |