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HAMAP rule MF_00732

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General rule information [?]

Accession MF_00732
Dates 21-NOV-2003 (Created)
7-FEB-2023 (Last updated, Version 29)
Name HTH_MntR
Bacteria; Bacilli
Template P54512 (MNTR_BACSU)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=HTH-type transcriptional regulator MntR;
AltName: Full=Manganese transport regulator;
Gene name

Comments [?]

Function Central regulator of manganese homeostasis.
Activity regulation DNA binding is strongly activated by Mn(2+).
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the DtxR/MntR family.

Keywords [?]

Gene Ontology [?]

GO:0030145; Molecular function: manganese ion binding.
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0030026; Biological process: intracellular manganese ion homeostasis.
GO:0006355; Biological process: regulation of DNA-templated transcription.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02742; Fe_dep_repr_C; 1;
PF01325; Fe_dep_repress; 1;
PROSITE PS50944; HTH_DTXR; 1; trigger=PRU00296;

Features [?]

From: MNTR_BACSU (P54512)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     8     8       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1     D  
BINDING     11     11       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2     E  
BINDING     77     77       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2     H  
BINDING     99     99       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1     E  
BINDING     99     99       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2     E  
BINDING     102     102       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1     E  
BINDING     102     102       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="2     E  
BINDING     103     103       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" /ligand_label="1     H  

Additional information [?]

Size range 130-170 amino acids
Related rules None
Fusion None