HAMAP rule MF_00735

General rule information [?]

Accession	MF_00735
Dates	24-NOV-2003 (Created) 1-JUN-2023 (Last updated, Version 21)

Name	Methyltr_PrmA

Scope

Bacteria

Templates

P0A8T1 (PRMA_ECOLI); Q84BQ9 (PRMA_THET8): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

PRMA

Protein name

RecName:		Full=Ribosomal protein L11 methyltransferase;
		Short=L11 Mtase;
		EC 2.1.1.-;

Gene name

prmA

Comments [?]

Function	Methylates ribosomal protein L11.
Catalytic activity	RHEA:54192: L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine
Subcellular location	Cytoplasm.
Similarity	Belongs to the methyltransferase superfamily. PrmA family.

Keywords [?]

Gene Ontology [?]

GO:0008276; Molecular function: protein methyltransferase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PIRSF	PIRSF000401; RPL11_MTase; 0-1;
NCBIfam	TIGR00406; PrmA; 1;

Features [?]

From: PRMA_THET8 (Q84BQ9)

Key From To Description Tag Condition FTGroup

BINDING 107 107 /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 T 1

BINDING 128 128 /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 G 1

BINDING 149 149 /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 D 1

BINDING 191 191 /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 N 1

Additional information [?]

Size range	220-400 amino acids
Related rules	None
Fusion	None
Comments	See: MEDLINE=20450294; PubMed=10997488; Bujnicki J.M.; "Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases."; Acta Microbiol. Pol. 49:19-29(2000).