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Annotation rule MF_00735
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General rule information [?]

Accession MF_00735
Dates 24-NOV-2003 (Created)
13-FEB-2020 (Last updated, Version 18)
Name Methyltr_PrmA
Scope
Bacteria
Templates P0A8T1 (PRMA_ECOLI); Q84BQ9 (PRMA_THET8): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PRMA
Protein name
RecName: Full=Ribosomal protein L11 methyltransferase;
Short=L11 Mtase;
EC 2.1.1.-;
Gene name
prmA

Comments [?]

Function Methylates ribosomal protein L11.
Catalytic activity RHEA:54192: L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine
Subcellular location Cytoplasm.
Similarity Belongs to the methyltransferase superfamily. PrmA family.

Keywords [?]


Gene Ontology [?]

GO:0008276; Molecular function: protein methyltransferase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PIRSF PIRSF000401; RPL11_MTase; 0-1;
TIGRFAMs TIGR00406; PrmA; 1;

Features [?]

From: PRMA_THET8 (Q84BQ9)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     107     107       S-adenosyl-L-methionine     T   1
BINDING     128     128       S-adenosyl-L-methionine; via carbonyl oxygen     G   1
BINDING     149     149       S-adenosyl-L-methionine     D   1
BINDING     191     191       S-adenosyl-L-methionine     N   1

Additional information [?]

Size range 220-400 amino acids
Related rules None
Fusion None
Comments See: MEDLINE=20450294; PubMed=10997488; Bujnicki J.M.; "Sequence, structural, and evolutionary analysis of prokaryotic ribosomal protein L11 methyltransferases."; Acta Microbiol. Pol. 49:19-29(2000).