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| Annotation rule MF_00742 |
General rule information
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| Accession | MF_00742 |
| Dates | 1-DEC-2003 (Created) 18-NOV-2019 (Last updated, Version 26) |
| Name | Formyl_CoA_transfer |
| Scope | Bacteria |
| Templates | P69902 (FCTA_ECOLI); O06644 (FCTA_OXAFO): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate. |
| Catalytic activity | RHEA:16545: formyl-CoA + oxalate = formate + oxalyl-CoA
EC 2.8.3.16 |
| Subunit | Homodimer. |
| Pathway | Metabolic intermediate degradation; oxalate degradation; CO(2) and formate from oxalate: step 1/2. |
| Similarity | Belongs to the CoA-transferase III family. Frc subfamily. |
Keywords
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Gene Ontology
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GO:0008410; Molecular function: CoA-transferase activity.
Cross-references
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Features
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| From: FCTA_OXAFO (O06644) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION (Optional) | 15 | 18 | Coenzyme A binding | H-x-Q-A | ||||||||
| REGION (Optional) | 72 | 75 | Coenzyme A binding | L-x-[MT]-K | ||||||||
| REGION (Optional) | 96 | 98 | Coenzyme A binding | N-x-[GAH] | ||||||||
| REGION (Optional) | 137 | 140 | Coenzyme A binding | K-x-Y-E | ||||||||
| REGION (Optional) | 260 | 262 | Substrate binding | G-G-Q | ||||||||
| ACT_SITE | 169 | 169 | Nucleophile | D | ||||||||
| BINDING | 38 | 38 | Coenzyme A | R | ||||||||
| BINDING (Optional) | 104 | 104 | Coenzyme A | [RH] | ||||||||
| From: FCTA_ECOLI (P69902) | ||||||||||||
| REGION (Optional) | 17 | 18 | Coenzyme A binding | Q-S | ||||||||
| REGION (Optional) | 273 | 275 | Coenzyme A binding | Q-E-x | ||||||||
Additional information
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| Size range | 409-428 amino acids |
| Related rules | None |
| Fusion | None |