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Annotation rule MF_00742
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General rule information [?]

Accession MF_00742
Dates 1-DEC-2003 (Created)
18-NOV-2019 (Last updated, Version 26)
Name Formyl_CoA_transfer
Scope
Bacteria
Templates P69902 (FCTA_ECOLI); O06644 (FCTA_OXAFO): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FCTA
Protein name
RecName: Full=Formyl-CoA:oxalate CoA-transferase;
Short=FCOCT;
EC 2.8.3.16;
AltName: Full=Formyl-coenzyme A transferase;
Short=Formyl-CoA transferase;
Gene name
frc

Comments [?]

Function Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
Catalytic activity RHEA:16545: formyl-CoA + oxalate = formate + oxalyl-CoA
EC 2.8.3.16
Subunit Homodimer.
Pathway Metabolic intermediate degradation; oxalate degradation; CO(2) and formate from oxalate: step 1/2.
Similarity Belongs to the CoA-transferase III family. Frc subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008410; Molecular function: CoA-transferase activity.

Cross-references [?]

Pfam PF02515; CoA_transf_3; 1;
TIGRFAMs TIGR03253; oxalate_frc; 1;

Features [?]

From: FCTA_OXAFO (O06644)
Key     From     To       Description   Tag   Condition   FTGroup
REGION (Optional)     15     18       Coenzyme A binding     H-x-Q-A  
REGION (Optional)     72     75       Coenzyme A binding     L-x-[MT]-K  
REGION (Optional)     96     98       Coenzyme A binding     N-x-[GAH]  
REGION (Optional)     137     140       Coenzyme A binding     K-x-Y-E  
REGION (Optional)     260     262       Substrate binding     G-G-Q  
ACT_SITE     169     169       Nucleophile     D  
BINDING     38     38       Coenzyme A     R  
BINDING (Optional)     104     104       Coenzyme A     [RH]  
From: FCTA_ECOLI (P69902)
REGION (Optional)     17     18       Coenzyme A binding     Q-S  
REGION (Optional)     273     275       Coenzyme A binding     Q-E-x  

Additional information [?]

Size range 409-428 amino acids
Related rules None
Fusion None