HAMAP rule MF_00744

General rule information [?]

Accession	MF_00744
Dates	10-DEC-2003 (Created) 26-JAN-2023 (Last updated, Version 23)

Name

MetJ

Scope

Bacteria; Pseudomonadota

Template

P0A8U6 (METJ_ECOLI)

Triggered by

HAMAP; MF_00744 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

METJ

Protein name

RecName:		Full=Met repressor;
AltName:		Full=Met regulon regulatory protein MetJ;

Gene name

metJ

Comments [?]

Function	This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
Subunit	Homodimer.
Subcellular location	Cytoplasm.
Domain	Does not bind DNA by a helix-turn-helix motif.
Similarity	Belongs to the MetJ family.

Keywords [?]

Cytoplasm
Amino-acid biosynthesis
Transcription
Transcription regulation
Repressor
Methionine biosynthesis
DNA-binding

Gene Ontology [?]

GO:0045892; Biological process: negative regulation of DNA-templated transcription.
GO:0009086; Biological process: methionine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF01340; MetJ; 1;

Additional information [?]

Size range	104-106 amino acids
Related rules	None
Fusion	None

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