HAMAP rule MF_00744
General rule information
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Accession | MF_00744 |
Dates | 10-DEC-2003 (Created) 26-JAN-2023 (Last updated, Version 23) |
Name | MetJ |
Scope | Bacteria; Pseudomonadota |
Template | P0A8U6 (METJ_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. |
Subunit | Homodimer. |
Subcellular location | Cytoplasm. |
Domain | Does not bind DNA by a helix-turn-helix motif. |
Similarity | Belongs to the MetJ family. |
Keywords
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Cytoplasm
Amino-acid biosynthesis
Transcription
Transcription regulation
Repressor
Methionine biosynthesis
DNA-binding
Amino-acid biosynthesis
Transcription
Transcription regulation
Repressor
Methionine biosynthesis
DNA-binding
Gene Ontology
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GO:0045892; Biological process: negative regulation of DNA-templated transcription.
GO:0009086; Biological process: methionine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0009086; Biological process: methionine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF01340; MetJ; 1; |
Additional information
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Size range | 104-106 amino acids |
Related rules | None |
Fusion | None |