HAMAP rule MF_00744
General rule information
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Accession | MF_00744 |
Dates | 10-DEC-2003 (Created)
26-JAN-2023 (Last updated, Version 23) |
Name | MetJ |
Scope(s) |
Bacteria Pseudomonadota |
Template(s) | P0A8U6 (METJ_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00744 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | METJ |
Protein name | RecName: Full=Met repressor; AltName: Full=Met regulon regulatory protein MetJ; |
Gene name | Name=metJ; |
Comments
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FUNCTION | This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. |
SUBUNIT | Homodimer. |
SUBCELLULAR LOCATION | Cytoplasm. |
DOMAIN | Does not bind DNA by a helix-turn-helix motif. |
SIMILARITY | Belongs to the MetJ family. |
Keywords
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Cytoplasm |
Amino-acid biosynthesis |
Transcription |
Transcription regulation |
Repressor |
Methionine biosynthesis |
DNA-binding |
Gene Ontology
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GO:0045892; Biological process:negative regulation of DNA-templated transcription |
GO:0009086; Biological process:methionine biosynthetic process |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Pfam | PF01340; MetJ; 1; |
Features
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Additional information
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Size range | 104-106 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |