HAMAP rule MF_00769

General rule information [?]

Accession	MF_00769
Dates	10-APR-2004 (Created) 2-NOV-2020 (Last updated, Version 18)
Name	2PGK
Scope(s)	Archaea Euryarchaeota
Template(s)	Q49156 (PGK2_METFV); [ Recover all ]
Triggered by	HAMAP; MF_00769 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PGK2
Protein name	RecName: Full=2-phosphoglycerate kinase; Short=2PGK; EC=2.7.2.16;
Gene name	Name=pgk2;

Comments [?]

FUNCTION	Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3- diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3- bisphosphoglycerate, a thermoprotectant.
CATALYTIC ACTIVITY	Reaction=(2R)-2-phosphoglycerate + ATP = (2R)-2,3-bisphosphoglycerate + ADP + H(+); Xref=Rhea:RHEA:42408, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58248, ChEBI:CHEBI:58289, ChEBI:CHEBI:456216; EC=2.7.2.16;
COFACTOR	Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
PATHWAY	Thermoadapter biosynthesis; cyclic 2,3-diphosphoglycerate biosynthesis; cyclic 2,3-diphosphoglycerate from 2-phospho-D-glycerate: step 1/2.
SIMILARITY	Belongs to the 2-phosphoglycerate kinase family.

Keywords [?]

Gene Ontology [?]

GO:0016774; Molecular function:phosphotransferase activity, carboxyl group as acceptor

Cross-references [?]

Pfam	PF03477; ATP-cone; 1;
PROSITE	PS51161; ATP_CONE; 1;

Features [?]

Additional information [?]