HAMAP rule MF_00770

General rule information [?]

Accession	MF_00770
Dates	13-APR-2004 (Created) 1-JUN-2023 (Last updated, Version 28)
Name	RhaD
Scope(s)	Bacteria
Template(s)	P32169 (RHAD_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00770 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RHAD
Protein name	RecName: Full=Rhamnulose-1-phosphate aldolase; EC=4.1.2.19;
Gene name	Name=rhaD;

Comments [?]

FUNCTION	Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
CATALYTIC ACTIVITY	Reaction=L-rhamnulose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate; Xref=Rhea:RHEA:19689, ChEBI:CHEBI:18041, ChEBI:CHEBI:57642, ChEBI:CHEBI:58313; EC=4.1.2.19;
case <FTGroup:1>
COFACTOR	Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
end case
PATHWAY	Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 3/3.
case <OC:Enterobacterales>
SUBUNIT	Homotetramer.
end case
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the aldolase class II family. RhaD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008994; Molecular function:rhamnulose-1-phosphate aldolase activity

GO:0019299; Biological process:rhamnose metabolic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF00596; Aldolase_II; 1;
NCBIfam	TIGR02624; rhamnu_1P_ald; 1;

Features [?]

From: RHAD_ECOLI (P32169)

Key

From

Description

Tag

Condition

FTGroup

ACT_SITE

117

BINDING

141

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"

BINDING

143

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"

BINDING

212

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"

Additional information [?]