HAMAP rule MF_00781
General rule information
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| Accession | MF_00781 |
| Dates | 3-MAY-2004 (Created)
17-FEB-2023 (Last updated, Version 18) |
| Name | HetR |
| Scope(s) |
Bacteria Cyanobacteriota |
| Template(s) | P27709 (HETR_NOSS1); [ Recover all ] |
| Triggered by |
HAMAP; MF_00781 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HETR |
| case <OC:Nostocales> | |
| Protein name | RecName: Full=DNA-binding transcriptional activator HetR; EC=3.4.21.-; AltName: Full=Heterocyst differentiation control protein; |
| else | |
| Protein name | RecName: Full=DNA-binding transcriptional activator HetR; EC=3.4.21.-; |
| end case | |
| Gene name | Name=hetR; |
Comments
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| case <OC:Nostocales> | |
| FUNCTION | Controls heterocyst differentiation. Dimerization is required for DNA-binding. Has both a protease and a DNA-binding activity. |
| else | |
| FUNCTION | Might be involved in temporal and/or spatial regulation of nitrogen fixation. Dimerization is required for DNA-binding. Has both a protease and a DNA-binding activity. |
| end case | |
| SUBUNIT | Homodimer; disulfide-linked. |
| SIMILARITY | Belongs to the peptidase S48 family. |
Keywords
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| Activator | |
| case <FT:2> | |
| Disulfide bond | |
| end case | |
| DNA-binding | |
| Hydrolase | |
| Protease | |
| Serine protease | |
| case <OC:Nostocales> | |
| Heterocyst | |
| end case | |
Gene Ontology
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| GO:0003677; Molecular function:DNA binding | |
| GO:0004252; Molecular function:serine-type endopeptidase activity | |
| case <OCellular component:Nostocales> | |
| GO:0043158; Biological process:heterocyst development | |
| end case | |
Cross-references
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| Pfam | PF03574; Peptidase_S48; 1; |
Features
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| From: HETR_NOSS1 (P27709) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 152 | 152 | S | |||||||||
| DISULFID | 48 | 48 | /note="Interchain" | C | ||||||||
Additional information
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| Size range | 298-302 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |