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HAMAP rule MF_00784

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General rule information [?]

Accession MF_00784
Dates 18-MAY-2004 (Created)
13-JAN-2023 (Last updated, Version 20)
Name AgrB
Scope(s) Bacteria
Template(s) P0C1P7 (AGRB_STAAU); [ Recover all ]
Triggered by HAMAP; MF_00784 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier AGRB
case <OC:Staphylococcus>
Protein name RecName: Full=Accessory gene regulator protein B;
Gene name Name=agrB;
end case
case not <OC:Staphylococcus>
Protein name RecName: Full=Putative AgrB-like protein;
end case

Comments [?]

case <OC:Staphylococcus>
FUNCTIONEssential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP.
end case
case not <OC:Staphylococcus>
FUNCTIONMay be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.
end case
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the AgrB family.

Keywords [?]

Gene Ontology [?]

GO:0008233; Molecular function:peptidase activity
GO:0009372; Biological process:quorum sensing
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF04647; AgrB; 1;
General Transmembrane; -; 3-5;

Features [?]

Additional information [?]

Size range 187-242 amino acids
Related rules None
Fusion Nter: None Cter: None

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