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HAMAP rule MF_00784

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General rule information [?]

Accession MF_00784
Dates 18-MAY-2004 (Created)
13-JAN-2023 (Last updated, Version 20)
Name AgrB
Scope
Bacteria; Bacillota
Template P0C1P7 (AGRB_STAAU)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
AGRB
case <OC:Staphylococcus>
Protein name
RecName: Full=Accessory gene regulator protein B;
EC 3.4.-.-;
Gene name
agrB
end case
case not <OC:Staphylococcus>
Protein name
RecName: Full=Putative AgrB-like protein;
EC 3.4.-.-;
end case

Comments [?]

case <OC:Staphylococcus>
Function Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP.
end case
case not <OC:Staphylococcus>
Function May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor.
end case
Subcellular location Cell membrane; Multi-pass membrane protein.
Similarity Belongs to the AgrB family.

Keywords [?]

Cell membrane
Membrane
Hydrolase
Protease
Quorum sensing
Transmembrane
case <OC:Staphylococcus>
Virulence
end case
Transmembrane helix

Gene Ontology [?]

GO:0008233; Molecular function: peptidase activity.
GO:0009372; Biological process: quorum sensing.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF04647; AgrB; 1;

Computed features [?]

General Transmembrane; -; 3-5; trigger=yes;

Additional information [?]

Size range 187-242 amino acids
Related rules None
Fusion None


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