HAMAP rule MF_00784
General rule information
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Accession | MF_00784 |
Dates | 18-MAY-2004 (Created) 13-JAN-2023 (Last updated, Version 20) |
Name | AgrB |
Scope | Bacteria; Bacillota |
Template | P0C1P7 (AGRB_STAAU) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
case <OC:Staphylococcus>
Protein name |
|
Gene name |
|
end case
case not <OC:Staphylococcus>
Protein name |
|
end case
Comments
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case <OC:Staphylococcus>
Function | Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP. |
end case
case not <OC:Staphylococcus>
Function | May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor. |
end case
Subcellular location | Cell membrane; Multi-pass membrane protein. |
Similarity | Belongs to the AgrB family. |
Keywords
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case <OC:Staphylococcus>
end case
Gene Ontology
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GO:0008233; Molecular function: peptidase activity.
GO:0009372; Biological process: quorum sensing.
GO:0005886; Cellular component: plasma membrane.
GO:0009372; Biological process: quorum sensing.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF04647; AgrB; 1; |
Computed features
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General | Transmembrane; -; 3-5; trigger=yes; |
Additional information
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Size range | 187-242 amino acids |
Related rules | None |
Fusion | None |