HAMAP rule MF_00796

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00796
Accession	MF_00796
Dates	28-FEB-2005 (Created) 02-SEP-2024 (Last updated, Version 21)
Name	NTPase_1
Scope(s)	Bacteria Aquificales Natranaerobiales Thermotogales Archaea
Template(s)	O67322; [ Recover all ]
Triggered by	HAMAP; MF_00796 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	NTPTH
Protein name	RecName: Full=Nucleoside-triphosphatase ; Short=NTPase; EC=3.6.1.15; AltName: Full=Nucleoside triphosphate phosphohydrolase;

Comments [?]

FUNCTION	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.
CATALYTIC ACTIVITY	Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'- diphosphate + phosphate + H(+); Xref=Rhea:RHEA:23680, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474, ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15;
SIMILARITY	Belongs to the THEP1 NTPase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0017111; Molecular function:ribonucleoside triphosphate phosphatase activity

Cross-references [?]

Pfam	PF03266; NTPase_1; 1;

Features [?]

From: NTPTH_AQUAE (O67322)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

G-x(2)-G-x(2)-K-x

BINDING

102

109

/ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

x(3)-[IMV]-D-E-[IVL]-G

Additional information [?]