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HAMAP rule MF_00807

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General rule information [?]

Accession MF_00807
Dates 3-MAR-2005 (Created)
28-NOV-2023 (Last updated, Version 17)
Name ACC_deaminase
Scope(s) Bacteria
Pseudomonadota
Template(s) Q5PWZ8 (1A1D_PSEPU); [ Recover all ]
Triggered by HAMAP; MF_00807 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier 1A1D
Protein name RecName: Full=1-aminocyclopropane-1-carboxylate deaminase;
                 Short=ACC deaminase;
                 Short=ACCD;
                 EC=3.5.99.7;
Gene name Name=acdS;

Comments [?]

FUNCTIONCatalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
CATALYTIC ACTIVITY Reaction=1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH4(+); Xref=Rhea:RHEA:16933, ChEBI:CHEBI:15377, ChEBI:CHEBI:16763, ChEBI:CHEBI:28938, ChEBI:CHEBI:58360; EC=3.5.99.7;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
SUBUNITHomotrimer.
SIMILARITYBelongs to the ACC deaminase/D-cysteine desulfhydrase family.

Keywords [?]


Gene Ontology [?]

GO:0008660; Molecular function:1-aminocyclopropane-1-carboxylate deaminase activity
GO:0018871; Biological process:1-aminocyclopropane-1-carboxylate metabolic process

Cross-references [?]

Pfam PF00291; PALP; 1;
NCBIfam TIGR01274; ACC_deam; 1;

Features [?]

From: 1A1D_PSEPU (Q5PWZ8)
Key From To Description Tag Condition FTGroup
ACT_SITE 78 78 /note="Nucleophile" S
MOD_RES 51 51 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 337-339 amino acids
Related rules None
Fusion Nter: None Cter: None



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