HAMAP rule MF_00807

General rule information [?]

Accession	MF_00807
Dates	3-MAR-2005 (Created) 26-JAN-2023 (Last updated, Version 15)

Name	ACC_deaminase

Scope

Bacteria; Pseudomonadota

Template

Q5PWZ8 (1A1D_PSEPU)

Triggered by

HAMAP; MF_00807 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

1A1D

Protein name

RecName:		Full=1-aminocyclopropane-1-carboxylate deaminase;
		Short=ACC deaminase;
		Short=ACCD;
		EC 3.5.99.7;

Gene name

acdS

Comments [?]

Function	Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
Catalytic activity	RHEA:16933: 1-aminocyclopropane-1-carboxylate + H2O = 2-oxobutanoate + NH4(+) EC 3.5.99.7
Cofactor	pyridoxal 5'-phosphate
Subunit	Homotrimer.
Similarity	Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

Keywords [?]

Hydrolase
Pyridoxal phosphate

Gene Ontology [?]

GO:0008660; Molecular function: 1-aminocyclopropane-1-carboxylate deaminase activity.
GO:0018871; Biological process: 1-aminocyclopropane-1-carboxylate metabolic process.

Cross-references [?]

Pfam	PF00291; PALP; 1;
TIGRFAMs	TIGR01274; ACC_deam; 1;

Features [?]

From: 1A1D_PSEPU (Q5PWZ8)

Key From To Description Tag Condition FTGroup

ACT_SITE 78 78 Nucleophile S

MOD_RES 51 51 N6-(pyridoxal phosphate)lysine K

Additional information [?]

Size range	337-339 amino acids
Related rules	None
Fusion	None

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