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Annotation rule MF_00830
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General rule information [?]

Accession MF_00830
Dates 2-NOV-2010 (Created)
7-JAN-2020 (Last updated, Version 10)
Name RutB
Scope
Bacteria
Template P75897 (RUTB_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RUTB
Protein name
RecName: Full=Ureidoacrylate amidohydrolase RutB;
EC 3.5.1.110;
Gene name
rutB

Comments [?]

Function Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
Catalytic activity RHEA:42624: (Z)-3-ureidoacrylate + H(+) + H2O = (Z)-3-aminoacrylate + CO2 + NH4(+)
EC 3.5.1.110
RHEA:42620: (Z)-2-methylureidoacrylate + H(+) + H2O = (Z)-2-methylaminoacrylate + CO2 + NH4(+)
EC 3.5.1.110
case <OC:Escherichia> or <OC:Shigella>
Induction Up-regulated by the nitrogen regulatory protein C (NtrC also called GlnG) and repressed by RutR.
end case
Similarity Belongs to the isochorismatase family. RutB subfamily.

Keywords [?]


Gene Ontology [?]

GO:0016811; Molecular function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides.
GO:0006212; Biological process: uracil catabolic process.
GO:0019740; Biological process: nitrogen utilization.

Cross-references [?]

Pfam PF00857; Isochorismatase; 1;
TIGRFAMs TIGR03614; RutB; 1;

Features [?]

From: RUTB_ECOLI (P75897)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     166     166       Nucleophile     C  

Additional information [?]

Size range 225-258 amino acids
Related rules None
Fusion None