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HAMAP rule MF_00839

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General rule information [?]

Accession MF_00839
Dates 25-APR-2016 (Created)
26-JAN-2023 (Last updated, Version 5)
Name HPF
Templates A2RIX0 (HPF_LACLM); A0A0H3GEZ8 (HPF_LISM4); P28368 (HPF_BACSU); Q2FIN9 (HPF_STAA3); P19954 (PRSP1_SPIOL): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Ribosome hibernation promoting factor;
Gene name

Comments [?]

Function Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
Subunit Interacts with 100S ribosomes.
Subcellular location Cytoplasm.
Similarity Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.

Keywords [?]

Gene Ontology [?]

GO:0006417; Biological process: regulation of translation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF16321; Ribosom_S30AE_C; 1;
PF02482; Ribosomal_S30AE; 1;
TIGRFAMs TIGR00741; yfiA; 1;

Additional information [?]

Size range 178-254 amino acids
Related rules None
Fusion None
Comments This family does not include the short paralogs (YfiA and short HPF) found in some Pseudomonadota as they have a slightly altered function. It encompasses a chloroplast-targeted protein but does not annotate it.