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HAMAP rule MF_00839

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General rule information [?]

Accession MF_00839
Dates 25-APR-2016 (Created)
1-JUN-2023 (Last updated, Version 6)
Name HPF
Scope(s) Bacteria
Template(s) A2RIX0 (HPF_LACLM); A0A0H3GEZ8 (HPF_LISM4); P28368 (HPF_BACSU); Q2FIN9 (HPF_STAA3); P19954 (PRSP1_SPIOL); [ Recover all ]
Triggered by HAMAP; MF_00839 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier HPF
Protein name RecName: Full=Ribosome hibernation promoting factor;
Gene name Name=hpf;

Comments [?]

FUNCTIONRequired for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
SUBUNITInteracts with 100S ribosomes.
SIMILARITYBelongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.

Keywords [?]

Gene Ontology [?]

GO:0006417; Biological process:regulation of translation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF16321; Ribosom_S30AE_C; 1;
Pfam PF02482; Ribosomal_S30AE; 1;
NCBIfam TIGR00741; yfiA; 1;

Features [?]

Additional information [?]

Size range 178-254 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments This family does not include the short paralogs (YfiA and short HPF) found in some Pseudomonadota as they have a slightly altered function. It encompasses a chloroplast-targeted protein but does not annotate it.

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