HAMAP rule MF_00839
General rule information
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| Accession | MF_00839 |
| Dates | 25-APR-2016 (Created)
1-JUN-2023 (Last updated, Version 6) |
| Name | HPF |
| Scope(s) |
Bacteria |
| Template(s) | A2RIX0 (HPF_LACLM); A0A0H3GEZ8 (HPF_LISM4); P28368 (HPF_BACSU); Q2FIN9 (HPF_STAA3); P19954 (PRSP1_SPIOL); [ Recover all ] |
| Triggered by |
HAMAP; MF_00839 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HPF |
| Protein name | RecName: Full=Ribosome hibernation promoting factor; Short=HPF; |
| Gene name | Name=hpf; |
Comments
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| FUNCTION | Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. |
| SUBUNIT | Interacts with 100S ribosomes. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily. |
Keywords
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Gene Ontology
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| GO:0006417; Biological process:regulation of translation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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| Size range | 178-254 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | This family does not include the short paralogs (YfiA and short HPF) found in some Pseudomonadota as they have a slightly altered function. It encompasses a chloroplast-targeted protein but does not annotate it. |