HAMAP rule MF_00839
General rule information
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Accession |
MF_00839 |
Dates |
25-APR-2016 (Created) 26-JAN-2023 (Last updated, Version 5) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Ribosome hibernation promoting factor;
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Short=HPF;
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Function |
Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. |
Subunit |
Interacts with 100S ribosomes. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily. |
GO:0006417; Biological process: regulation of translation.
GO:0005737; Cellular component: cytoplasm.
Additional information
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Size range |
178-254 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
This family does not include the short paralogs (YfiA and short HPF) found in some Pseudomonadota as they have a slightly altered function. It encompasses a chloroplast-targeted protein but does not annotate it. |