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Annotation rule MF_00848
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General rule information [?]

Accession MF_00848
Dates 2-DEC-2019 (Created)
9-JUL-2020 (Last updated, Version 3)
Name Uup
Scope
Bacteria
Template P43672 (UUP_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
UUP
Protein name
RecName: Full=ATP-binding protein Uup;
EC 3.6.1.-;
Gene name
uup

Comments [?]

Function Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.
Catalytic activity RHEA:13065: ATP + H2O = ADP + H(+) + phosphate
Subcellular location Cytoplasm. Note=Associates with ribosomes.
Similarity Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.

Keywords [?]

ATP-binding
case <Feature:coiled>
Coiled coil
end case
Cytoplasm
DNA-binding
DNA repair
DNA damage
Hydrolase
Nucleotide-binding
Repeat

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0016887; Molecular function: ATPase activity.
GO:0005737; Cellular component: cytoplasm.
GO:0003677; Molecular function: DNA binding.
GO:0043022; Molecular function: ribosome binding.

Cross-references [?]

PROSITE PS00211; ABC_TRANSPORTER_1; 1-2;
PS50893; ABC_TRANSPORTER_2; 2;
Pfam PF00005; ABC_tran; 2;
PF16326; ABC_tran_CTD; 0-1;
PF12848; ABC_tran_Xtn; 0-1;

Computed features [?]

General Coiled_coil; -; 0-unlimited;

Features [?]

From: UUP_ECOLI (P43672)
Key     From     To       Description   Tag   Condition   FTGroup
DOMAIN     1     253       ABC transporter 1        
DOMAIN     320     546       ABC transporter 2        
NP_BIND     36     43       ATP 1     G-x-N-G-[ACESTV]-G-[KQ]-[ST]  
NP_BIND     352     359       ATP 2     G-x-[NS]-[GA]-[ACISTV]-G-K-[ST]  

Additional information [?]

Size range 582-686 amino acids
Related rules None
Fusion None


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