HAMAP rule MF_00848

General rule information [?]

Accession	MF_00848
Dates	2-DEC-2019 (Created) 3-SEP-2024 (Last updated, Version 8)
Name	Uup
Scope(s)	Bacteria
Template(s)	P43672 (UUP_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00848 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	UUP
Protein name	RecName: Full=ATP-binding protein Uup; EC=3.6.1.-;
Gene name	Name=uup;

Comments [?]

FUNCTION	Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.
CATALYTIC ACTIVITY	Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
SUBCELLULAR LOCATION	Cytoplasm. Note=Associates with ribosomes.
SIMILARITY	Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0016887; Molecular function:ATP hydrolysis activity

GO:0005737; Cellular component:cytoplasm

GO:0003677; Molecular function:DNA binding

GO:0043022; Molecular function:ribosome binding

Cross-references [?]

Features [?]

From: UUP_ECOLI (P43672)

Key

From

Description

Tag

Condition

FTGroup

DOMAIN

253

/note="ABC transporter 1"

DOMAIN

320

546

/note="ABC transporter 2"

BINDING

/ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
/ligand_label="1"

G-x-N-G-[ACESTV]-G-[KQ]-[ST]

BINDING

352

359

/ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
/ligand_label="2"

G-x-[NS]-[GA]-[ACISTV]-G-K-[ST]

Additional information [?]