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HAMAP rule MF_00848

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General rule information [?]

Accession MF_00848
Dates 2-DEC-2019 (Created)
19-NOV-2022 (Last updated, Version 7)
Name Uup
Scope(s) Bacteria
Template(s) P43672 (UUP_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00848 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier UUP
Protein name RecName: Full=ATP-binding protein Uup;
Gene name Name=uup;

Comments [?]

FUNCTIONProbably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.
CATALYTIC ACTIVITY Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
SUBCELLULAR LOCATIONCytoplasm. Note=Associates with ribosomes.
SIMILARITYBelongs to the ABC transporter superfamily. ABCF family. Uup subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0016887; Molecular function:ATP hydrolysis activity
GO:0005737; Cellular component:cytoplasm
GO:0003677; Molecular function:DNA binding
GO:0043022; Molecular function:ribosome binding

Cross-references [?]

Pfam PF00005; ABC_tran; 2;
Pfam PF16326; ABC_tran_CTD; 0-1;
Pfam PF12848; ABC_tran_Xtn; 0-1;
General Coiled_coil; -; 0-unlimited;

Features [?]

From: UUP_ECOLI (P43672)
Key From To Description Tag Condition FTGroup
DOMAIN 1 253 /note="ABC transporter 1"
DOMAIN 320 546 /note="ABC transporter 2"
BINDING 36 43 /ligand="ATP"
BINDING 352 359 /ligand="ATP"

Additional information [?]

Size range 582-686 amino acids
Related rules None
Fusion Nter: None Cter: None

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