HAMAP rule MF_00856
General rule information
[?]
Accession | MF_00856 |
Dates | 1-SEP-2020 (Created) 17-FEB-2023 (Last updated, Version 3) |
Name | Raf1 |
Scope | Bacteria; Cyanobacteriota |
Templates | Q8YLP6 (RAF1_NOSS1); Q31Q05 (RAF1_SYNE7); Q8DI26 (RAF1_THEVB): [Recover all] |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Gene name |
|
Comments
[?]
Function | A major RuBisCO chaperone. Acts after GroEL-GroES chaperonin to fold and/or assemble the large subunit of RuBisCO (ccbL, rbcL). Cooperates with RbcX in RbcL folding, plays the major role in assembly of dimers into RbcL(8)-Raf1(8) intermediate complexes. RbcS replaces Raf1, leading to holoenzyme formation. |
Subunit | Homodimer. Forms an RbcL(8)-Raf1(8) complex. Forms complexes of many stoichiometries with RbcL with and without RbcS. RbcX and Raf1 can bind simultaneously to RbcL. |
Subcellular location | Cytoplasm. |
Domain | Has 3 domains, the N-terminal alpha-helical domain, an extended flexible linker and the C-terminal beta-sheet domain. The 2 C-terminal beta-sheet domains are swapped and pack against each other to form the dimer interface. |
Similarity | Belongs to the RAF family. |
Keywords
[?]
Gene Ontology
[?]
GO:0015977; Biological process: carbon fixation.
GO:0005737; Cellular component: cytoplasm.
GO:0110102; Biological process: ribulose bisphosphate carboxylase complex assembly.
GO:0005737; Cellular component: cytoplasm.
GO:0110102; Biological process: ribulose bisphosphate carboxylase complex assembly.
Cross-references
[?]
Features
[?]
From: RAF1_NOSS1 (Q8YLP6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | 16 | 197 | N-terminal alpha-helix | |||||||||
REGION | 221 | 347 | C-terminal beta-sheet |
Additional information
[?]
Size range | 335-380 amino acids |
Related rules | None |
Fusion | None |