HAMAP rule MF_00864

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00864
Accession	MF_00864
Dates	24-JUN-2021 (Created) 21-MAR-2025 (Last updated, Version 6)
Name	RNApol_arch_Rpo4
Scope(s)	Archaea
Template(s)	Q4JB12; B8YB58; Q7LXK4; [ Recover all ]
Triggered by	HAMAP; MF_00864 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RPO4
Protein name	RecName: Full=DNA-directed RNA polymerase subunit Rpo4; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase subunit F;
Gene name	Name=rpo4; Synonyms=rpoF;

Comments [?]

FUNCTION	DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
CATALYTIC ACTIVITY	Reaction=RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate; Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.6;
SUBUNIT	Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the eukaryotic RPB4 RNA polymerase subunit family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:0003899; Molecular function:DNA-directed RNA polymerase activity

GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

Pfam	PF03874; RNA_pol_Rpb4; 1;
PIRSF	PIRSF005053; RNA_pol_F_arch; 0-1;

Features [?]

Additional information [?]