HAMAP rule MF_00865

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00865
Accession	MF_00865
Dates	24-JUN-2021 (Created) 21-MAR-2025 (Last updated, Version 7)
Name	RNApol_arch_Rpo7
Scope(s)	Archaea
Template(s)	B8YB57; P39466; Q57840; Q980A3; [ Recover all ]
Triggered by	HAMAP; MF_00865 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	RPO7
Protein name	RecName: Full=DNA-directed RNA polymerase subunit Rpo7; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase subunit E;
Gene name	Name=rpo7; Synonyms=rpoE;

Comments [?]

FUNCTION	DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
CATALYTIC ACTIVITY	Reaction=RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate; Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.6;
SUBUNIT	Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.
SUBCELLULAR LOCATION	Cytoplasm.
DOMAIN	Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
SIMILARITY	Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm

GO:0003899; Molecular function:DNA-directed RNA polymerase activity

GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

Features [?]

Additional information [?]