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HAMAP rule MF_00865

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General rule information [?]

Accession MF_00865
Dates 24-JUN-2021 (Created)
1-JUN-2023 (Last updated, Version 4)
Name RNApol_arch_Rpo7
Scope(s) Archaea
Template(s) B8YB57 (RPO7_SACSH); P39466 (RPO7_SULAC); Q57840 (RPO7_METJA); Q980A3 (RPO7_SACS2); [ Recover all ]
Triggered by HAMAP; MF_00865 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RPO7
Protein name RecName: Full=DNA-directed RNA polymerase subunit Rpo7;
                 EC=2.7.7.6;
AltName: Full=DNA-directed RNA polymerase subunit E;
Gene name Name=rpo7; Synonyms=rpoE;

Comments [?]

FUNCTIONDNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
CATALYTIC ACTIVITY Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.6;
SUBUNITPart of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.
SUBCELLULAR LOCATIONCytoplasm.
DOMAINForms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
SIMILARITYBelongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.

Keywords [?]


Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm
GO:0003899; Molecular function:DNA-directed 5'-3' RNA polymerase activity
GO:0006351; Biological process:DNA-templated transcription

Cross-references [?]

PROSITE PS50126; S1; 1;
Pfam PF00575; S1; 1;
Pfam PF03876; SHS2_Rpb7-N; 0-1;
NCBIfam TIGR00448; rpoE; 1;

Features [?]


Additional information [?]

Size range 158-244 amino acids
Related rules None
Fusion Nter: None Cter: None



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