HAMAP rule MF_00904
General rule information
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| Accession | MF_00904 |
| Dates | 10-AUG-2011 (Created)
29-SEP-2022 (Last updated, Version 5) |
| Name | Modulator_MzrA |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P42615 (MZRA_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00904 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MZRA |
| Protein name | RecName: Full=Modulator protein MzrA; |
| Gene name | Name=mzrA; |
Comments
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| FUNCTION | Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. |
| SUBUNIT | Interacts with EnvZ. |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| SIMILARITY | Belongs to the MzrA family. |
Keywords
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Gene Ontology
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| GO:0019901; Molecular function:protein kinase binding |
| GO:0045859; Biological process:regulation of protein kinase activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| General | Transmembrane; -; 1; |
| ADD_TOPO_DOMAIN | Cytoplasmic; -; 1; |
| ADD_TOPO_DOMAIN | Periplasmic; -; 1; |
Features
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Additional information
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| Size range | 110-138 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |