HAMAP rule MF_00907
General rule information
[?]
Accession | MF_00907 |
Dates | 29-SEP-2011 (Created) 1-JUN-2023 (Last updated, Version 6) |
Name | Thioesterase_EntH |
Scope | Bacteria; Enterobacterales |
Template | P0A8Y8 (ENTH_ECOLI) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Gene name |
|
Comments
[?]
Function | Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. |
Pathway | Siderophore biosynthesis; enterobactin biosynthesis. |
Subunit | Homotetramer. Dimer of dimers. Interacts specifically with the aryl carrier protein (ArCP) domain of EntB. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the thioesterase PaaI family. |
Keywords
[?]
Gene Ontology
[?]
GO:0016790; Molecular function: thiolester hydrolase activity.
GO:0009239; Biological process: enterobactin biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0009239; Biological process: enterobactin biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Cross-references
[?]
Features
[?]
From: ENTH_ECOLI (P0A8Y8) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
ACT_SITE | 63 | 63 | Nucleophile or proton acceptor | E |
Additional information
[?]
Size range | 137-139 amino acids |
Related rules | None |
Fusion | None |