HAMAP rule MF_00909
General rule information
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| Accession | MF_00909 |
| Dates | 21-OCT-2011 (Created) 1-JUN-2023 (Last updated, Version 14) |
| Name | FtsZ |
| Scope | Bacteria
Archaea |
| Templates | P0A9A6 (FTSZ_ECOLI); P17865 (FTSZ_BACSU); P9WN95 (FTSZ_MYCTU); Q48327 (FTSZ1_HALVD); Q9V2S6 (FTSZ_HALMT); P0A029 (FTSZ_STAAM): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. |
| Subunit | Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. |
| Subcellular location | Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane. |
| Similarity | Belongs to the FtsZ family. |
Keywords
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Gene Ontology
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GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.
GO:0090529; Biological process: cell septum assembly.
GO:0043093; Biological process: FtsZ-dependent cytokinesis.
GO:0051258; Biological process: protein polymerization.
GO:0032153; Cellular component: cell division site.
GO:0005737; Cellular component: cytoplasm.
GO:0003924; Molecular function: GTPase activity.
GO:0090529; Biological process: cell septum assembly.
GO:0043093; Biological process: FtsZ-dependent cytokinesis.
GO:0051258; Biological process: protein polymerization.
GO:0032153; Cellular component: cell division site.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| PROSITE | PS01134; FTSZ_1; 1; |
| PS01135; FTSZ_2; 1; | |
| Pfam | PF00091; Tubulin; 1; |
| PRINTS | PR00423; CELLDVISFTSZ; 1; |
| NCBIfam | TIGR00065; FtsZ; 1; |
| TIGR03483; FtsZ_alphas_C; 0-1; |
Features
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| From: FTSZ_STAAM (P0A029) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 21 | 25 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | G-[GA]-G-x-N | ||||||||
| BINDING | 108 | 110 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | G-[TS]-G | ||||||||
| BINDING (Optional) | 139 | 139 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | E | ||||||||
| BINDING (Optional) | 143 | 143 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | [RK] | ||||||||
| BINDING (Optional) | 187 | 187 | /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565 | [DN] | ||||||||
Additional information
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| Size range | 320-700 amino acids |
| Related rules | None |
| Fusion | None |