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Annotation rule MF_00909
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General rule information [?]

Accession MF_00909
Dates 21-OCT-2011 (Created)
19-NOV-2019 (Last updated, Version 11)
Name FtsZ
Templates P0A9A6 (FTSZ_ECOLI); P17865 (FTSZ_BACSU); P9WN95 (FTSZ_MYCTU); Q48327 (FTSZ1_HALVD); Q9V2S6 (FTSZ_HALMT); P0A029 (FTSZ_STAAM): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Cell division protein FtsZ;
Gene name

Comments [?]

Function Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Subunit Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
Subcellular location Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Similarity Belongs to the FtsZ family.

Keywords [?]

Gene Ontology [?]

GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.
GO:0090529; Biological process: cell septum assembly.
GO:0043093; Biological process: FtsZ-dependent cytokinesis.
GO:0051258; Biological process: protein polymerization.
GO:0032153; Cellular component: cell division site.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS01134; FTSZ_1; 1;
PS01135; FTSZ_2; 1;
Pfam PF00091; Tubulin; 1;
TIGRFAMs TIGR00065; FtsZ; 1;
TIGR03483; FtsZ_alphas_C; 0-1;

Features [?]

From: FTSZ_STAAM (P0A029)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     21     25       GTP     G-[GA]-G-x-N  
NP_BIND     108     110       GTP     G-[TS]-G  
BINDING (Optional)     139     139       GTP     E  
BINDING (Optional)     143     143       GTP     [RK]  
BINDING (Optional)     187     187       GTP     [DN]  

Additional information [?]

Size range 320-700 amino acids
Related rules None
Fusion None