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HAMAP rule MF_00909

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General rule information [?]

Accession MF_00909
Dates 21-OCT-2011 (Created)
1-JUN-2023 (Last updated, Version 14)
Name FtsZ
Scope(s) Bacteria
Template(s) P0A9A6 (FTSZ_ECOLI); P17865 (FTSZ_BACSU); P9WN95 (FTSZ_MYCTU); Q48327 (FTSZ1_HALVD); Q9V2S6 (FTSZ_HALMT); P0A029 (FTSZ_STAAM); [ Recover all ]
Triggered by HAMAP; MF_00909 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier FTSZ
Protein name RecName: Full=Cell division protein FtsZ;
Gene name Name=ftsZ;

Comments [?]

FUNCTIONEssential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
SUBUNITHomodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
SUBCELLULAR LOCATIONCytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
SIMILARITYBelongs to the FtsZ family.

Keywords [?]

Gene Ontology [?]

GO:0005525; Molecular function:GTP binding
GO:0003924; Molecular function:GTPase activity
GO:0090529; Biological process:cell septum assembly
GO:0043093; Biological process:FtsZ-dependent cytokinesis
GO:0051258; Biological process:protein polymerization
GO:0032153; Cellular component:cell division site
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS01134; FTSZ_1; 1;
PROSITE PS01135; FTSZ_2; 1;
Pfam PF00091; Tubulin; 1;
NCBIfam TIGR00065; FtsZ; 1;
NCBIfam TIGR03483; FtsZ_alphas_C; 0-1;

Features [?]

From: FTSZ_STAAM (P0A029)
Key From To Description Tag Condition FTGroup
BINDING 21 25 /ligand="GTP"
BINDING 108 110 /ligand="GTP"
BINDING 139 139 /ligand="GTP"
BINDING 143 143 /ligand="GTP"
BINDING 187 187 /ligand="GTP"

Additional information [?]

Size range 320-700 amino acids
Related rules None
Fusion Nter: None Cter: None

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