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HAMAP rule MF_00909

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General rule information [?]

Accession MF_00909
Dates 21-OCT-2011 (Created)
1-JUN-2023 (Last updated, Version 14)
Name FtsZ
Scope
Bacteria
Archaea
Templates P0A9A6 (FTSZ_ECOLI); P17865 (FTSZ_BACSU); P9WN95 (FTSZ_MYCTU); Q48327 (FTSZ1_HALVD); Q9V2S6 (FTSZ_HALMT); P0A029 (FTSZ_STAAM): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FTSZ
Protein name
RecName: Full=Cell division protein FtsZ;
Gene name
ftsZ

Comments [?]

Function Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
Subunit Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
Subcellular location Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Similarity Belongs to the FtsZ family.

Keywords [?]


Gene Ontology [?]

GO:0005525; Molecular function: GTP binding.
GO:0003924; Molecular function: GTPase activity.
GO:0090529; Biological process: cell septum assembly.
GO:0043093; Biological process: FtsZ-dependent cytokinesis.
GO:0051258; Biological process: protein polymerization.
GO:0032153; Cellular component: cell division site.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS01134; FTSZ_1; 1;
PS01135; FTSZ_2; 1;
Pfam PF00091; Tubulin; 1;
PRINTS PR00423; CELLDVISFTSZ; 1;
NCBIfam TIGR00065; FtsZ; 1;
TIGR03483; FtsZ_alphas_C; 0-1;

Features [?]

From: FTSZ_STAAM (P0A029)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     21     25       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     G-[GA]-G-x-N  
BINDING     108     110       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     G-[TS]-G  
BINDING (Optional)     139     139       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     E  
BINDING (Optional)     143     143       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     [RK]  
BINDING (Optional)     187     187       /ligand="GTP" /ligand_id="ChEBI:CHEBI:37565     [DN]  

Additional information [?]

Size range 320-700 amino acids
Related rules None
Fusion None