HAMAP rule MF_00921
General rule information
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| Accession | MF_00921 |
| Dates | 13-APR-2012 (Created)
3-SEP-2024 (Last updated, Version 10) |
| Name | PDRP |
| Scope(s) |
Bacteria |
| Template(s) | Q195N6 (PDRP1_MAIZE); [ Recover all ] |
| Triggered by |
HAMAP; MF_00921 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PDRP |
| Protein name | RecName: Full=Putative pyruvate, phosphate dikinase regulatory protein; Short=PPDK regulatory protein; EC=2.7.11.32; EC=2.7.4.27; |
Comments
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| FUNCTION | Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. |
| CATALYTIC ACTIVITY | Reaction=N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + ADP = N(tele)-phospho-L-histidyl/O-phospho-L-threonyl- [pyruvate, phosphate dikinase] + AMP + H(+); Xref=Rhea:RHEA:43692, Rhea:RHEA-COMP:10650, Rhea:RHEA-COMP:10651, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:61977, ChEBI:CHEBI:83586, ChEBI:CHEBI:456215, ChEBI:CHEBI:456216; EC=2.7.11.32; |
| CATALYTIC ACTIVITY | Reaction=N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + phosphate + H(+) = N(tele)-phospho-L- histidyl/L-threonyl-[pyruvate, phosphate dikinase] + diphosphate; Xref=Rhea:RHEA:43696, Rhea:RHEA-COMP:10650, Rhea:RHEA-COMP:10651, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:33019, ChEBI:CHEBI:43474, ChEBI:CHEBI:61977, ChEBI:CHEBI:83586; EC=2.7.4.27; |
| SIMILARITY | Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily. |
Keywords
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Gene Ontology
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| GO:0004674; Molecular function:protein serine/threonine kinase activity |
| GO:0016776; Molecular function:phosphotransferase activity, phosphate group as acceptor |
| GO:0043531; Molecular function:ADP binding |
| GO:0006468; Biological process:protein phosphorylation |
| GO:0006470; Biological process:protein dephosphorylation |
Cross-references
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| Pfam | PF03618; Kinase-PPPase; 1; |
| PIRSF | PIRSF038149; Pyruvate_Pi_dikinase_regulator; 1; |
Features
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| From: PDRP_BACSU (P54470) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 151 | 158 | /ligand="ADP" /ligand_id="ChEBI:CHEBI:456216" |
[GA]-x-[SP]-R-x-[GSC]-K-[TS] | ||||||||
Additional information
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| Size range | 211-471 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |