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Annotation rule MF_00930 |
Accession | MF_00930 |
Dates | 7-JAN-2013 (Created) 19-NOV-2019 (Last updated, Version 4) |
Name | GreB |
Scope | Bacteria |
Template | P30128 (GREB_ECOLI) |
Triggered by |
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Protein name |
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Gene name |
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Function | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. |
Similarity | Belongs to the GreA/GreB family. GreB subfamily. |
PROSITE | PS00829; GREAB_1; 1; |
PS00830; GREAB_2; 1; | |
Pfam | PF01272; GreA_GreB; 1; |
PF03449; GreA_GreB_N; 1; | |
TIGRFAMs | TIGR01461; greB; 1; |
PIRSF | PIRSF006092; GreA_GreB; 1; |
General | Coiled_coil; -; 0-unlimited; trigger=yes; |
Size range | 138-240 amino acids |
Related rules | MF_00105 (GREA) |
Fusion | None |