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HAMAP rule MF_00931

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General rule information [?]

Accession MF_00931
Dates 7-JAN-2013 (Created)
1-JUN-2023 (Last updated, Version 10)
Name Aldeh_decarbonylase
Scope(s) Bacteria
Cyanobacteriota
Template(s) Q54764 (ALDEC_SYNE7); B2J1M1 (ALDEC_NOSP7); Q7V6D4 (ALDEC_PROMM); Q55688 (ALDEC_SYNY3); [ Recover all ]
Triggered by HAMAP; MF_00931 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ALDEC
Protein name RecName: Full=Aldehyde decarbonylase;
                 Short=AD;
                 EC=4.1.99.5;
AltName: Full=Fatty aldehyde decarbonylase;

Comments [?]

FUNCTIONCatalyzes the decarbonylation of fatty aldehydes to alkanes.
CATALYTIC ACTIVITY Reaction=a long-chain fatty aldehyde + H(+) + 2 NADPH + O2 = a long- chain alkane + formate + H2O + 2 NADP(+); Xref=Rhea:RHEA:21440, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:15740, ChEBI:CHEBI:17176, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:83563; EC=4.1.99.5;
case <FTGroup:1>
COFACTOR Note=Binds 2 metal cations per subunit. The catalytic dinuclear metal- binding site could be either a di-iron or a manganese-iron cofactor.;
end case
SIMILARITYBelongs to the aldehyde decarbonylase family.

Keywords [?]

Lyase
NADP
case <FTGroup:1>
Iron
Metal-binding
end case

Gene Ontology [?]

GO:0009924; Molecular function:octadecanal decarbonylase activity
case <FTGroup:1>
GO:0046914; Molecular function:transition metal ion binding
end case

Cross-references [?]

Pfam PF11266; DUF3066; 1;
NCBIfam TIGR04059; Ald_deCOase; 1;

Features [?]

From: ALDEC_PROMM (Q7V6D4)
Key From To Description Tag Condition FTGroup
BINDING 45 45 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
E 1
BINDING 73 73 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
E 1
BINDING 73 73 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
E 1
BINDING 76 76 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="1"
H 1
BINDING 128 128 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
E 1
BINDING 160 160 /ligand="Fe cation"
/ligand_id="ChEBI:CHEBI:24875"
/ligand_label="2"
H 1

Additional information [?]

Size range 226-254 amino acids
Related rules None
Fusion Nter: None Cter: None



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