HAMAP rule MF_00931
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00931 |
| Accession | MF_00931 |
| Dates | 07-JAN-2013 (Created)
03-SEP-2024 (Last updated, Version 13) |
| Name | Aldeh_decarbonylase |
| Scope(s) |
Bacteria Cyanobacteriota |
| Template(s) | Q54764; B2J1M1; Q7V6D4; Q55688; [ Recover all ] |
| Triggered by |
HAMAP; MF_00931 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ALDEC |
| Protein name | RecName: Full=Aldehyde decarbonylase; Short=AD; EC=4.1.99.5; AltName: Full=Fatty aldehyde decarbonylase; |
Comments
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| FUNCTION | Catalyzes the decarbonylation of fatty aldehydes to alkanes. |
| CATALYTIC ACTIVITY | Reaction=a long-chain fatty aldehyde + 2 NADPH + O2 + H(+) = a long- chain alkane + formate + 2 NADP(+) + H2O; Xref=Rhea:RHEA:21440, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:15740, ChEBI:CHEBI:17176, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:83563; EC=4.1.99.5; |
| case <FTGroup:1> | |
| COFACTOR | Note=Binds 2 metal cations per subunit. The catalytic dinuclear metal- binding site could be either a di-iron or a manganese-iron cofactor.; |
| end case | |
| SIMILARITY | Belongs to the aldehyde decarbonylase family. |
Keywords
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| Lyase | |
| NADP | |
| case <FTGroup:1> | |
| Iron | |
| Metal-binding | |
| end case | |
Gene Ontology
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| GO:0071771; Molecular function:aldehyde oxygenase (deformylating) activity | |
| case <FTGroup:1> | |
| GO:0046914; Molecular function:transition metal ion binding | |
| end case | |
Cross-references
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Features
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| From: ALDEC_PROMM (Q7V6D4) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 45 | 45 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
E | 1 | |||||||
| BINDING | 73 | 73 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
E | 1 | |||||||
| BINDING | 73 | 73 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
E | 1 | |||||||
| BINDING | 76 | 76 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="1" |
H | 1 | |||||||
| BINDING | 128 | 128 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
E | 1 | |||||||
| BINDING | 160 | 160 | /ligand="Fe cation" /ligand_id="ChEBI:CHEBI:24875" /ligand_label="2" |
H | 1 | |||||||
Additional information
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| Size range | 226-254 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |