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HAMAP rule MF_00945

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General rule information [?]

Accession MF_00945
Dates 28-FEB-2013 (Created)
1-JUN-2023 (Last updated, Version 8)
Name NusA
Scope(s) Bacteria
Template(s) P0AFF6 (NUSA_ECOLI); [ Recover all ]
Triggered by
case c? <OC:Bacteria>
HAMAP; MF_00945_B (Get profile general information and statistics)
end case
case c? <OC:Archaea>
HAMAP; MF_00945_A (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NUSA
case <OC:Bacteria>
Protein name RecName: Full=Transcription termination/antitermination protein NusA;
else case <OC:Archaea>
Protein name RecName: Full=Probable transcription termination protein NusA;
end case
Gene name Name=nusA;

Comments [?]

case <OC:Bacteria>
FUNCTIONParticipates in both transcription termination and antitermination.
SUBUNITMonomer. Binds directly to the core enzyme of the DNA- dependent RNA polymerase and to nascent RNA.
else case <OC:Archaea>
FUNCTIONParticipates in transcription termination.
end case
SIMILARITYBelongs to the NusA family.

Keywords [?]

Gene Ontology [?]

case <OCellular component:Bacteria>
GO:0003723; Molecular function:RNA binding
GO:0031564; Biological process:transcription antitermination
end case
GO:0006353; Biological process:DNA-templated transcription termination
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS50084; KH_TYPE_1; 0-2;
PROSITE PS50126; S1; 0-1;
Pfam PF13184; KH_5; 1;
Pfam PF08529; NusA_N; 1;
Pfam PF00575; S1; 1;
Pfam PF00013; KH_1; 1;
Pfam PF07650; KH_2; 1;
NCBIfam TIGR01953; NusA; 0-1;
NCBIfam TIGR01954; nusA_Cterm_rpt; 0-2;
NCBIfam TIGR01952; nusA_arch; 0-1;

Features [?]

Key From To Description Tag Condition FTGroup
case <OC:Enterobacterales>
REPEAT 364 414 /note="1"
REPEAT 439 489 /note="2"
REGION 364 489 /note="2 X 51 AA approximate repeats"
end case

Additional information [?]

Size range 130-600 amino acids
Related rules None
Fusion Nter: None Cter: None

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