HAMAP rule MF_00945
General rule information
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| Accession | MF_00945 |
| Dates | 28-FEB-2013 (Created)
1-JUN-2023 (Last updated, Version 8) |
| Name | NusA |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P0AFF6 (NUSA_ECOLI); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria>
HAMAP; MF_00945_B (Get profile general information and statistics) end case
case c? <OC:Archaea>
HAMAP; MF_00945_A (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NUSA |
| case <OC:Bacteria> | |
| Protein name | RecName: Full=Transcription termination/antitermination protein NusA; |
| else case <OC:Archaea> | |
| Protein name | RecName: Full=Probable transcription termination protein NusA; |
| end case | |
| Gene name | Name=nusA; |
Comments
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| case <OC:Bacteria> | |
| FUNCTION | Participates in both transcription termination and antitermination. |
| SUBUNIT | Monomer. Binds directly to the core enzyme of the DNA- dependent RNA polymerase and to nascent RNA. |
| else case <OC:Archaea> | |
| FUNCTION | Participates in transcription termination. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the NusA family. |
Keywords
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| Cytoplasm | |
| Transcription | |
| Transcription regulation | |
| Transcription termination | |
| case <OC:Bacteria> | |
| RNA-binding | |
| Transcription antitermination | |
| end case | |
| case <OC:Enterobacterales> | |
| Repeat | |
| end case | |
Gene Ontology
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| case <OCellular component:Bacteria> | |
| GO:0003723; Molecular function:RNA binding | |
| GO:0031564; Biological process:transcription antitermination | |
| end case | |
| GO:0006353; Biological process:DNA-templated transcription termination | |
| GO:0005737; Cellular component:cytoplasm | |
Cross-references
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| PROSITE | PS50084; KH_TYPE_1; 0-2; |
| PROSITE | PS50126; S1; 0-1; |
| Pfam | PF13184; KH_5; 1; |
| Pfam | PF08529; NusA_N; 1; |
| Pfam | PF00575; S1; 1; |
| Pfam | PF00013; KH_1; 1; |
| Pfam | PF07650; KH_2; 1; |
| NCBIfam | TIGR01953; NusA; 0-1; |
| NCBIfam | TIGR01954; nusA_Cterm_rpt; 0-2; |
| NCBIfam | TIGR01952; nusA_arch; 0-1; |
Features
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| From: NUSA_ECOLI (P0AFF6) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Enterobacterales> | ||||||||||||
| REPEAT | 364 | 414 | /note="1" | |||||||||
| REPEAT | 439 | 489 | /note="2" | |||||||||
| REGION | 364 | 489 | /note="2 X 51 AA approximate repeats" | |||||||||
| end case | ||||||||||||
Additional information
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| Size range | 130-600 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |