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HAMAP rule MF_00945

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General rule information [?]

Accession MF_00945
Dates 28-FEB-2013 (Created)
1-JUN-2023 (Last updated, Version 8)
Name NusA
Template P0AFF6 (NUSA_ECOLI)
case <OC:Bacteria>
end case

case <OC:Archaea>
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Bacteria>
Protein name
RecName: Full=Transcription termination/antitermination protein NusA;
else case <OC:Archaea>
Protein name
RecName: Full=Probable transcription termination protein NusA;
end case
Gene name

Comments [?]

case <OC:Bacteria>
Function Participates in both transcription termination and antitermination.
Subunit Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
else case <OC:Archaea>
Function Participates in transcription termination.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the NusA family.

Keywords [?]

case <OC:Bacteria>
end case
case <OC:Enterobacterales>
end case

Gene Ontology [?]

case <OC:Bacteria>
GO:0003723; Molecular function: RNA binding.
GO:0031564; Biological process: transcription antitermination.
end case
GO:0006353; Biological process: DNA-templated transcription termination.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS50084; KH_TYPE_1; 0-2; trigger=PRU00117;
PS50126; S1; 0-1; trigger=PRU00180;
Pfam PF13184; KH_5; 1;
PF08529; NusA_N; 1;
PF00575; S1; 1;
PF00013; KH_1; 1;
PF07650; KH_2; 1;
NCBIfam TIGR01953; NusA; 0-1;
TIGR01954; nusA_Cterm_rpt; 0-2;
TIGR01952; nusA_arch; 0-1;

Features [?]

case <OC:Enterobacterales>
Key     From     To       Description   Tag   Condition   FTGroup
REPEAT     364     414       1        
REPEAT     439     489       2        
REGION     364     489       2 X 51 AA approximate repeats        
end case

Additional information [?]

Size range 130-600 amino acids
Related rules None
Fusion None