HAMAP logo

HAMAP rule MF_00946

Send feedback

General rule information [?]

Accession MF_00946
Dates 4-MAR-2013 (Created)
26-JAN-2023 (Last updated, Version 6)
Name HdeA
Scope(s) Bacteria
Template(s) P0AES9 (HDEA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00946 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier HDEA
case <OC:Enterobacterales>
Protein name RecName: Full=Acid stress chaperone HdeA;
Protein name RecName: Full=Probable acid stress chaperone HdeA;
end case
Gene name Name=hdeA;

Comments [?]

FUNCTIONRequired for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.
SIMILARITYBelongs to the HdeA family.

Keywords [?]

case <FTTag:disulf>
Disulfide bond
end case

Gene Ontology [?]

GO:1990451; Biological process:cellular stress response to acidic pH
GO:0042597; Cellular component:periplasmic space

Cross-references [?]

Pfam PF06411; HdeA; 1;
PIRSF PIRSF009564; HNS-dep_expression_A; 1;
General Signal; -; 1;

Features [?]

Key From To Description Tag Condition FTGroup
DISULFID 39 87 disulf C-x*-C

Additional information [?]

Size range 93-127 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)