HAMAP rule MF_00946
General rule information
[?]
Accession | MF_00946 |
Dates | 4-MAR-2013 (Created)
26-JAN-2023 (Last updated, Version 6) |
Name | HdeA |
Scope(s) |
Bacteria Pseudomonadota |
Template(s) | P0AES9 (HDEA_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00946 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | HDEA |
case <OC:Enterobacterales> | |
Protein name | RecName: Full=Acid stress chaperone HdeA; |
else | |
Protein name | RecName: Full=Probable acid stress chaperone HdeA; |
end case | |
Gene name | Name=hdeA; |
Comments
[?]
FUNCTION | Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins. |
SUBCELLULAR LOCATION | Periplasm. |
SIMILARITY | Belongs to the HdeA family. |
Keywords
[?]
Chaperone | |
case <FTTag:disulf> | |
Disulfide bond | |
end case | |
Periplasm |
Gene Ontology
[?]
GO:1990451; Biological process:cellular stress response to acidic pH |
GO:0042597; Cellular component:periplasmic space |
Cross-references
[?]
Pfam | PF06411; HdeA; 1; |
PIRSF | PIRSF009564; HNS-dep_expression_A; 1; |
General | Signal; -; 1; |
Features
[?]
From: HDEA_ECOLI (P0AES9) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DISULFID | 39 | 87 | disulf | C-x*-C |
Additional information
[?]
Size range | 93-127 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |