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Annotation rule MF_00946
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General rule information [?]

Accession MF_00946
Dates 4-MAR-2013 (Created)
19-NOV-2019 (Last updated, Version 5)
Name HdeA
Scope
Bacteria; Proteobacteria
Template P0AES9 (HDEA_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HDEA
case <OC:Enterobacterales>
Protein name
RecName: Full=Acid stress chaperone HdeA;
else
Protein name
RecName: Full=Probable acid stress chaperone HdeA;
end case
Gene name
hdeA

Comments [?]

Function Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.
Subcellular location Periplasm.
Similarity Belongs to the HdeA family.

Keywords [?]

Chaperone
case <FTTag:disulf>
Disulfide bond
end case
Periplasm

Gene Ontology [?]

GO:1990451; Biological process: cellular stress response to acidic pH.
GO:0042597; Cellular component: periplasmic space.

Cross-references [?]

Pfam PF06411; HdeA; 1;
PIRSF PIRSF009564; HNS-dep_expression_A; 1;

Computed features [?]

General Signal; -; 1; trigger=yes;

Features [?]

From: HDEA_ECOLI (P0AES9)
Key     From     To       Description   Tag   Condition   FTGroup
DISULFID     39     87           disulf   C-x*-C  

Additional information [?]

Size range 93-127 amino acids
Related rules None
Fusion None


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