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HAMAP rule MF_00948

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General rule information [?]

Accession MF_00948
Dates 7-MAR-2013 (Created)
1-JUN-2023 (Last updated, Version 7)
Name NusG
Scope(s) Bacteria
Template(s) P0AFG0 (NUSG_ECOLI); O67757 (NUSG_AQUAE); P29397 (NUSG_THEMA); Q06795 (NUSG_BACSU); [ Recover all ]
Triggered by HAMAP; MF_00948 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NUSG
Protein name RecName: Full=Transcription termination/antitermination protein NusG;
Gene name Name=nusG;

Comments [?]

case <OC:Enterobacterales>
FUNCTIONParticipates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.
SUBUNITMonomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
FUNCTIONParticipates in transcription elongation, termination and antitermination.
end case
SIMILARITYBelongs to the NusG family.

Keywords [?]

Gene Ontology [?]

GO:0006354; Biological process:DNA-templated transcription elongation
GO:0006353; Biological process:DNA-templated transcription termination
GO:0031564; Biological process:transcription antitermination

Cross-references [?]

Pfam PF00467; KOW; 1;
Pfam PF02357; NusG; 1;
NCBIfam TIGR00922; nusG; 0-1;
NCBIfam TIGR01956; NusG_myco; 0-1;

Features [?]

Additional information [?]

Size range 150-400 amino acids
Related rules None
Fusion Nter: None Cter: None

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