HAMAP rule MF_00948
General rule information
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Accession | MF_00948 |
Dates | 7-MAR-2013 (Created)
1-JUN-2023 (Last updated, Version 7) |
Name | NusG |
Scope(s) |
Bacteria |
Template(s) | P0AFG0 (NUSG_ECOLI); O67757 (NUSG_AQUAE); P29397 (NUSG_THEMA); Q06795 (NUSG_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_00948 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | NUSG |
Protein name | RecName: Full=Transcription termination/antitermination protein NusG; |
Gene name | Name=nusG; |
Comments
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case <OC:Enterobacterales> | |
FUNCTION | Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination. |
SUBUNIT | Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase. |
else | |
FUNCTION | Participates in transcription elongation, termination and antitermination. |
end case | |
SIMILARITY | Belongs to the NusG family. |
Keywords
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Gene Ontology
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GO:0006354; Biological process:DNA-templated transcription elongation |
GO:0006353; Biological process:DNA-templated transcription termination |
GO:0031564; Biological process:transcription antitermination |
Cross-references
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PROSITE | PS01014; NUSG; 1; |
Pfam | PF00467; KOW; 1; |
Pfam | PF02357; NusG; 1; |
PRINTS | PR00338; NUSGTNSCPFCT; 1; |
NCBIfam | TIGR00922; nusG; 0-1; |
NCBIfam | TIGR01956; NusG_myco; 0-1; |
Features
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Additional information
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Size range | 150-400 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |