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Annotation rule MF_00948
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General rule information [?]

Accession MF_00948
Dates 7-MAR-2013 (Created)
19-NOV-2019 (Last updated, Version 5)
Name NusG
Scope
Bacteria
Templates P0AFG0 (NUSG_ECOLI); O67757 (NUSG_AQUAE); P29397 (NUSG_THEMA); Q06795 (NUSG_BACSU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NUSG
Protein name
RecName: Full=Transcription termination/antitermination protein NusG;
Gene name
nusG

Comments [?]

case <OC:Enterobacterales>
Function Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.
Subunit Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
else
Function Participates in transcription elongation, termination and antitermination.
end case
Similarity Belongs to the NusG family.

Keywords [?]


Gene Ontology [?]

GO:0006354; Biological process: DNA-templated transcription, elongation.
GO:0006353; Biological process: DNA-templated transcription, termination.
GO:0031564; Biological process: transcription antitermination.

Cross-references [?]

PROSITE PS01014; NUSG; 1;
Pfam PF00467; KOW; 1; trigger=Yes;
PF02357; NusG; 1;
PRINTS PR00338; NUSGTNSCPFCT; 1;
TIGRFAMs TIGR00922; nusG; 0-1;
TIGR01956; NusG_myco; 0-1;

Additional information [?]

Size range 150-400 amino acids
Related rules None
Fusion None