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HAMAP rule MF_00957

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General rule information [?]

Accession MF_00957
Dates 22-APR-2013 (Created)
27-JUL-2023 (Last updated, Version 8)
Name PolyA_pol
Scope(s) Bacteria
Template(s) P0ABF1 (PCNB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00957 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PCNB
Protein name RecName: Full=Poly(A) polymerase I;
                 Short=PAP I;
Gene name Name=pcnB;

Comments [?]

FUNCTIONAdds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
CATALYTIC ACTIVITY Reaction=ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide; Xref=Rhea:RHEA:11332, Rhea:RHEA-COMP:14527, Rhea:RHEA-COMP:17347, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:140395, ChEBI:CHEBI:173115; EC=;
SIMILARITYBelongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:1990817; Molecular function:poly(A) RNA polymerase activity
GO:0003723; Molecular function:RNA binding

Cross-references [?]

Pfam PF01743; PolyA_pol; 1;
Pfam PF12626; PolyA_pol_arg_C; 1;
NCBIfam TIGR01942; pcnB; 1;

Features [?]

Key From To Description Tag Condition FTGroup
ACT_SITE 80 80 D
ACT_SITE 82 82 D
ACT_SITE 162 162 D

Additional information [?]

Size range 390-600 amino acids
Related rules None
Fusion Nter: None Cter: None

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