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Annotation rule MF_00957
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General rule information [?]

Accession MF_00957
Dates 22-APR-2013 (Created)
8-JUN-2021 (Last updated, Version 5)
Name PolyA_pol
Scope
Bacteria
Template P0ABF1 (PCNB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PCNB
Protein name
RecName: Full=Poly(A) polymerase I;
Short=PAP I;
EC 2.7.7.19;
Gene name
pcnB

Comments [?]

Function Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
Catalytic activity RHEA:11332: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide
EC 2.7.7.19
Similarity Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

Keywords [?]

ATP-binding
mRNA processing
Nucleotide-binding
RNA-binding
Transcription
Transferase

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004652; Molecular function: polynucleotide adenylyltransferase activity.
GO:0003723; Molecular function: RNA binding.
GO:0043631; Biological process: RNA polyadenylation.

Cross-references [?]

Pfam PF01743; PolyA_pol; 1;
PF12626; PolyA_pol_arg_C; 1;
TIGRFAMs TIGR01942; pcnB; 1;

Features [?]

From: PCNB_ECOLI (P0ABF1)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     80     80             D  
ACT_SITE     82     82             D  
ACT_SITE     162     162             D  

Additional information [?]

Size range 390-600 amino acids
Related rules None
Fusion None


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