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HAMAP rule MF_00958

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General rule information [?]

Accession MF_00958
Dates 26-APR-2013 (Created)
19-NOV-2019 (Last updated, Version 5)
Name RssB
Scope(s) Bacteria
Template(s) P0AEV1 (RSSB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00958 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RSSB
Protein name RecName: Full=Regulator of RpoS;
Gene name Name=rssB;

Comments [?]

FUNCTIONRegulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
SUBUNITBinds to RpoS.
case <FTTag:phospho>
PTMPhosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
end case
SIMILARITYBelongs to the RssB family.

Keywords [?]

case <FTTag:phospho>
end case
Stress response

Gene Ontology [?]

GO:0045862; Biological process:positive regulation of proteolysis
GO:0010468; Biological process:regulation of gene expression

Cross-references [?]

Pfam PF00072; Response_reg; 1;

Features [?]

Key From To Description Tag Condition FTGroup
MOD_RES 58 58 /note="4-aspartylphosphate" phospho D

Additional information [?]

Size range 330-370 amino acids
Related rules None
Fusion Nter: None Cter: None

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