HAMAP rule MF_00958
General rule information
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Accession | MF_00958 |
Dates | 26-APR-2013 (Created) 19-NOV-2019 (Last updated, Version 5) |
Name | RssB |
Scope | Bacteria; Enterobacterales |
Template | P0AEV1 (RSSB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. |
Subunit | Binds to RpoS. |
case <FTTag:phospho>
Ptm | Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS. |
end case
Similarity | Belongs to the RssB family. |
Keywords
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case <FTTag:phospho>
end case
Gene Ontology
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GO:0045862; Biological process: positive regulation of proteolysis.
GO:0010468; Biological process: regulation of gene expression.
GO:0010468; Biological process: regulation of gene expression.
Cross-references
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Features
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From: RSSB_ECOLI (P0AEV1) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOD_RES | 58 | 58 | 4-aspartylphosphate | phospho | D |
Additional information
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Size range | 330-370 amino acids |
Related rules | None |
Fusion | None |