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HAMAP rule MF_00959

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General rule information [?]

Accession MF_00959
Dates 30-APR-2013 (Created)
1-JUN-2023 (Last updated, Version 12)
Name Sigma70_RpoS
Scope(s) Bacteria
Template(s) P13445 (RPOS_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00959 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RPOS
Protein name RecName: Full=RNA polymerase sigma factor RpoS;
AltName: Full=Sigma S;
AltName: Full=Sigma-38;
Gene name Name=rpoS;

Comments [?]

FUNCTIONSigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
SUBUNITInteracts with the RNA polymerase core enzyme.
SIMILARITYBelongs to the sigma-70 factor family. RpoS subfamily.

Keywords [?]

Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0016987; Molecular function:sigma factor activity
GO:0010468; Biological process:regulation of gene expression
GO:0006352; Biological process:DNA-templated transcription initiation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS00715; SIGMA70_1; 1;
PROSITE PS00716; SIGMA70_2; 1;
Pfam PF00140; Sigma70_r1_2; 1;
Pfam PF04542; Sigma70_r2; 1;
Pfam PF04539; Sigma70_r3; 1;
Pfam PF04545; Sigma70_r4; 1;
NCBIfam TIGR02394; rpoS_proteo; 1;
NCBIfam TIGR02937; sigma70-ECF; 1;

Features [?]

From: RPOS_ECOLI (P13445)
Key From To Description Tag Condition FTGroup
DNA_BIND 288 307 /note="H-T-H motif"
REGION 56 89 /note="Sigma-70 factor domain-1"
REGION 94 164 /note="Sigma-70 factor domain-2"
REGION 174 249 /note="Sigma-70 factor domain-3"
REGION 262 315 /note="Sigma-70 factor domain-4"
MOTIF 118 121 /note="Interaction with polymerase core subunit RpoC" D-L-[IV]-[ED]

Additional information [?]

Size range 250-400 amino acids
Related rules None
Fusion Nter: None Cter: None

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