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Annotation rule MF_00959
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General rule information [?]

Accession MF_00959
Dates 30-APR-2013 (Created)
19-NOV-2019 (Last updated, Version 8)
Name Sigma70_RpoS
Scope
Bacteria; Proteobacteria
Template P13445 (RPOS_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RPOS
Protein name
RecName: Full=RNA polymerase sigma factor RpoS;
AltName: Full=Sigma S;
AltName: Full=Sigma-38;
Gene name
rpoS

Comments [?]

Function Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
Subunit Interacts with the RNA polymerase core enzyme.
Subcellular location Cytoplasm.
Similarity Belongs to the sigma-70 factor family. RpoS subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0001123; Biological process: transcription initiation from bacterial-type RNA polymerase promoter.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS00715; SIGMA70_1; 1;
PS00716; SIGMA70_2; 1;
Pfam PF00140; Sigma70_r1_2; 1;
PF04542; Sigma70_r2; 1;
PF04539; Sigma70_r3; 1;
PF04545; Sigma70_r4; 1;
PRINTS PR00046; SIGMA70FCT; 1;
TIGRFAMs TIGR02394; rpoS_proteo; 1;
TIGR02937; sigma70-ECF; 1;

Features [?]

From: RPOS_ECOLI (P13445)
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     288     307       H-T-H motif        
REGION     56     89       Sigma-70 factor domain-1        
REGION     94     164       Sigma-70 factor domain-2        
REGION     174     249       Sigma-70 factor domain-3        
REGION     262     315       Sigma-70 factor domain-4        
MOTIF     118     121       Interaction with polymerase core subunit RpoC     D-L-[IV]-[ED]  

Additional information [?]

Size range 250-400 amino acids
Related rules None
Fusion None