HAMAP logo

HAMAP rule MF_00961

Send feedback

General rule information [?]

Accession MF_00961
Dates 22-MAY-2013 (Created)
1-JUN-2023 (Last updated, Version 11)
Name Sigma70_RpoH
Bacteria; Pseudomonadota
Template P0AGB3 (RPOH_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=RNA polymerase sigma factor RpoH;
AltName: Full=RNA polymerase sigma-32 factor;
Gene name

Comments [?]

Function Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
Subunit Interacts with the RNA polymerase core enzyme.
Subcellular location Cytoplasm.
Similarity Belongs to the sigma-70 factor family. RpoH subfamily.

Keywords [?]

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0009408; Biological process: response to heat.
GO:0006352; Biological process: DNA-templated transcription initiation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS00715; SIGMA70_1; 1;
PS00716; SIGMA70_2; 1;
Pfam PF00140; Sigma70_r1_2; 0-1;
PF04542; Sigma70_r2; 1;
PF04545; Sigma70_r4; 1;
NCBIfam TIGR02392; rpoH_proteo; 1;
TIGR02937; sigma70-ECF; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     253     272       H-T-H motif        
REGION     53     122       Sigma-70 factor domain-2        
REGION     228     280       Sigma-70 factor domain-4        
MOTIF     77     80       Interaction with polymerase core subunit RpoC     [DE]-[LVIM]-[IVM]-[QSA]  

Additional information [?]

Size range 250-406 amino acids
Related rules None
Fusion None