HAMAP rule MF_00961
General rule information
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Accession | MF_00961 |
Dates | 22-MAY-2013 (Created) 1-JUN-2023 (Last updated, Version 11) |
Name | Sigma70_RpoH |
Scope | Bacteria; Pseudomonadota |
Template | P0AGB3 (RPOH_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. |
Subunit | Interacts with the RNA polymerase core enzyme. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the sigma-70 factor family. RpoH subfamily. |
Keywords
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Gene Ontology
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GO:0003677; Molecular function: DNA binding.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0009408; Biological process: response to heat.
GO:0006352; Biological process: DNA-templated transcription initiation.
GO:0005737; Cellular component: cytoplasm.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0009408; Biological process: response to heat.
GO:0006352; Biological process: DNA-templated transcription initiation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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PROSITE | PS00715; SIGMA70_1; 1; |
PS00716; SIGMA70_2; 1; | |
Pfam | PF00140; Sigma70_r1_2; 0-1; |
PF04542; Sigma70_r2; 1; | |
PF04545; Sigma70_r4; 1; | |
PRINTS | PR00046; SIGMA70FCT; 1; |
NCBIfam | TIGR02392; rpoH_proteo; 1; |
TIGR02937; sigma70-ECF; 1; |
Features
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From: RPOH_ECOLI (P0AGB3) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DNA_BIND | 253 | 272 | H-T-H motif | |||||||||
REGION | 53 | 122 | Sigma-70 factor domain-2 | |||||||||
REGION | 228 | 280 | Sigma-70 factor domain-4 | |||||||||
MOTIF | 77 | 80 | Interaction with polymerase core subunit RpoC | [DE]-[LVIM]-[IVM]-[QSA] |
Additional information
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Size range | 250-406 amino acids |
Related rules | None |
Fusion | None |