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Annotation rule MF_00961
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General rule information [?]

Accession MF_00961
Dates 22-MAY-2013 (Created)
19-NOV-2019 (Last updated, Version 7)
Name Sigma70_RpoH
Scope
Bacteria; Proteobacteria
Template P0AGB3 (RPOH_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RPOH
Protein name
RecName: Full=RNA polymerase sigma factor RpoH;
AltName: Full=RNA polymerase sigma-32 factor;
Gene name
rpoH

Comments [?]

Function Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
Subunit Interacts with the RNA polymerase core enzyme.
Subcellular location Cytoplasm.
Similarity Belongs to the sigma-70 factor family. RpoH subfamily.

Keywords [?]

Cytoplasm
DNA-binding
Sigma factor
Stress response
Transcription
Transcription regulation

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0009408; Biological process: response to heat.
GO:0001123; Biological process: transcription initiation from bacterial-type RNA polymerase promoter.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS00715; SIGMA70_1; 1;
PS00716; SIGMA70_2; 1;
Pfam PF00140; Sigma70_r1_2; 0-1;
PF04542; Sigma70_r2; 1;
PF04545; Sigma70_r4; 1;
PRINTS PR00046; SIGMA70FCT; 1;
TIGRFAMs TIGR02392; rpoH_proteo; 1;
TIGR02937; sigma70-ECF; 1;

Features [?]

From: RPOH_ECOLI (P0AGB3)
Key     From     To       Description   Tag   Condition   FTGroup
DNA_BIND     253     272       H-T-H motif        
REGION     53     122       Sigma-70 factor domain-2        
REGION     228     280       Sigma-70 factor domain-4        
MOTIF     77     80       Interaction with polymerase core subunit RpoC     [DE]-[LVIM]-[IVM]-[QSA]  

Additional information [?]

Size range 250-406 amino acids
Related rules None
Fusion None


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