HAMAP rule MF_00962
General rule information
[?]
Accession | MF_00962 |
Dates | 27-MAY-2013 (Created)
1-JUN-2023 (Last updated, Version 10) |
Name | Sigma70_FliA |
Scope(s) |
Bacteria Pseudomonadota |
Template(s) | P0AEM6 (FLIA_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00962 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier | FLIA |
Protein name | RecName: Full=RNA polymerase sigma factor FliA; AltName: Full=RNA polymerase sigma factor for flagellar operon; AltName: Full=Sigma F; AltName: Full=Sigma-28; |
Gene name | Name=fliA; |
Comments
[?]
FUNCTION | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the sigma-70 factor family. FliA subfamily. |
Keywords
[?]
Gene Ontology
[?]
GO:0003677; Molecular function:DNA binding |
GO:0016987; Molecular function:sigma factor activity |
GO:0010468; Biological process:regulation of gene expression |
GO:0006352; Biological process:DNA-templated transcription initiation |
GO:0005737; Cellular component:cytoplasm |
Cross-references
[?]
PROSITE | PS00715; SIGMA70_1; 1; |
PROSITE | PS00716; SIGMA70_2; 1; |
Pfam | PF04542; Sigma70_r2; 1; |
Pfam | PF04539; Sigma70_r3; 1; |
Pfam | PF04545; Sigma70_r4; 1; |
PRINTS | PR00046; SIGMA70FCT; 1; |
NCBIfam | TIGR02479; FliA_WhiG; 1; |
NCBIfam | TIGR02937; sigma70-ECF; 1; |
Features
[?]
From: FLIA_ECOLI (P0AEM6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DNA_BIND | 207 | 226 | /note="H-T-H motif" | |||||||||
REGION | 16 | 88 | /note="Sigma-70 factor domain-2" | |||||||||
REGION | 96 | 166 | /note="Sigma-70 factor domain-3" | |||||||||
REGION | 185 | 233 | /note="Sigma-70 factor domain-4" | |||||||||
MOTIF | 43 | 46 | /note="Interaction with polymerase core subunit RpoC" | D-[LMI]-[LIVMT]-Q |
Additional information
[?]
Size range | 207-306 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |