HAMAP logo

HAMAP rule MF_00962

Send feedback

General rule information [?]

Accession MF_00962
Dates 27-MAY-2013 (Created)
1-JUN-2023 (Last updated, Version 10)
Name Sigma70_FliA
Scope(s) Bacteria
Pseudomonadota
Template(s) P0AEM6 (FLIA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00962 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier FLIA
Protein name RecName: Full=RNA polymerase sigma factor FliA;
AltName: Full=RNA polymerase sigma factor for flagellar operon;
AltName: Full=Sigma F;
AltName: Full=Sigma-28;
Gene name Name=fliA;

Comments [?]

FUNCTIONSigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the sigma-70 factor family. FliA subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function:DNA binding
GO:0016987; Molecular function:sigma factor activity
GO:0010468; Biological process:regulation of gene expression
GO:0006352; Biological process:DNA-templated transcription initiation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS00715; SIGMA70_1; 1;
PROSITE PS00716; SIGMA70_2; 1;
Pfam PF04542; Sigma70_r2; 1;
Pfam PF04539; Sigma70_r3; 1;
Pfam PF04545; Sigma70_r4; 1;
PRINTS PR00046; SIGMA70FCT; 1;
NCBIfam TIGR02479; FliA_WhiG; 1;
NCBIfam TIGR02937; sigma70-ECF; 1;

Features [?]

From: FLIA_ECOLI (P0AEM6)
Key From To Description Tag Condition FTGroup
DNA_BIND 207 226 /note="H-T-H motif"
REGION 16 88 /note="Sigma-70 factor domain-2"
REGION 96 166 /note="Sigma-70 factor domain-3"
REGION 185 233 /note="Sigma-70 factor domain-4"
MOTIF 43 46 /note="Interaction with polymerase core subunit RpoC" D-[LMI]-[LIVMT]-Q

Additional information [?]

Size range 207-306 amino acids
Related rules None
Fusion Nter: None Cter: None



View rule in raw text format (no links)