HAMAP rule MF_00962
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00962 |
| Accession | MF_00962 |
| Dates | 27-MAY-2013 (Created)
01-JUN-2023 (Last updated, Version 11) |
| Name | Sigma70_FliA |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P0AEM6; [ Recover all ] |
| Triggered by |
HAMAP; MF_00962 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | FLIA |
| Protein name | RecName: Full=RNA polymerase sigma factor FliA; AltName: Full=RNA polymerase sigma factor for flagellar operon; AltName: Full=Sigma F; AltName: Full=Sigma-28; |
| Gene name | Name=fliA; |
Comments
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| FUNCTION | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the sigma-70 factor family. FliA subfamily. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0016987; Molecular function:sigma factor activity |
| GO:0010468; Biological process:regulation of gene expression |
| GO:0006352; Biological process:DNA-templated transcription initiation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| PROSITE | PS00715; SIGMA70_1; 1; |
| PROSITE | PS00716; SIGMA70_2; 1; |
| Pfam | PF04542; Sigma70_r2; 1; |
| Pfam | PF04539; Sigma70_r3; 1; |
| Pfam | PF04545; Sigma70_r4; 1; |
| PRINTS | PR00046; SIGMA70FCT; 1; |
| NCBIfam | TIGR02479; FliA_WhiG; 1; |
| NCBIfam | TIGR02937; sigma70-ECF; 1; |
Features
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| From: FLIA_ECOLI (P0AEM6) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | 207 | 226 | /note="H-T-H motif" | |||||||||
| REGION | 16 | 88 | /note="Sigma-70 factor domain-2" | |||||||||
| REGION | 96 | 166 | /note="Sigma-70 factor domain-3" | |||||||||
| REGION | 185 | 233 | /note="Sigma-70 factor domain-4" | |||||||||
| MOTIF | 43 | 46 | /note="Interaction with polymerase core subunit RpoC" | D-[LMI]-[LIVMT]-Q | ||||||||
Additional information
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| Size range | 207-306 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |