HAMAP rule MF_00974

General rule information [?]

Accession	MF_00974
Dates	16-OCT-2013 (Created) 1-JUN-2023 (Last updated, Version 7)

Name	DNA_primase_DnaG

Scope

Bacteria

Templates

P0ABS5 (DNAG_ECOLI); O67465 (DNAG_AQUAE); Q9X4D0 (DNAG_GEOSE): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

DNAG

Protein name

RecName:		Full=DNA primase;
		EC 2.7.7.101;

Gene name

dnaG

Comments [?]

Function	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
Catalytic activity	Reaction=ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.; EC=2.7.7.101;
Subunit	Monomer. Interacts with DnaB.

case <FTTag:zinc>

Cofactor	Zn(2+) Note: Binds 1 zinc ion per monomer.
Domain	Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.

end case

Similarity

Belongs to the DnaG primase family.

Keywords [?]

case <FTTag:zinc>

end case

Gene Ontology [?]

GO:0003896; Molecular function: DNA primase activity.

case <FTTag:zinc>

GO:0008270; Molecular function: zinc ion binding.

end case

GO:0006269; Biological process: DNA replication, synthesis of RNA primer.

Cross-references [?]

Features [?]

From: DNAG_ECOLI (P0ABS5)

Key From To Description Tag Condition FTGroup

ZN_FING 40 64 CHC2-type zinc C-x(2)-H-x(17,18)-C-x(2,3)-C

Additional information [?]