HAMAP rule MF_00975
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00975 |
| Accession | MF_00975 |
| Dates | 24-OCT-2013 (Created)
19-NOV-2022 (Last updated, Version 6) |
| Name | Exosome_Csl4 |
| Scope(s) |
Archaea |
| Template(s) | Q980J9; O30033; [ Recover all ] |
| Triggered by |
HAMAP; MF_00975 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CSL4 |
| Protein name | RecName: Full=Exosome complex component Csl4; |
| Gene name | Name=csl4; |
Comments
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| FUNCTION | Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. |
| SUBUNIT | Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the CSL4 family. |
Keywords
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| Cytoplasm | |
| Exosome | |
| case <FTGroup:1> | |
| Metal-binding | |
| Zinc | |
| end case | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0008270; Molecular function:zinc ion binding | |
| end case | |
| GO:0006401; Biological process:RNA catabolic process | |
| GO:0005737; Cellular component:cytoplasm | |
Cross-references
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Features
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| From: CSL4_ARCFU (O30033) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 143 | 143 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 146 | 146 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 159 | 159 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 162 | 162 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
Additional information
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| Size range | 176-362 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |