HAMAP rule MF_00975
General rule information
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Accession | MF_00975 |
Dates | 24-OCT-2013 (Created) 19-NOV-2022 (Last updated, Version 5) |
Name | Exosome_Csl4 |
Scope | Archaea |
Templates | Q980J9 (CSL4_SACS2); O30033 (CSL4_ARCFU): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. |
Subunit | Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the CSL4 family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
Cross-references
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PROSITE | PS50126; S1; 1; trigger=PRU00180; |
Pfam | PF14382; ECR1_N; 1; |
PF00575; S1; 1; | |
PF10447; EXOSC1; 1; |
Features
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From: CSL4_ARCFU (O30033) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 143 | 143 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
BINDING | 146 | 146 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
BINDING | 159 | 159 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 | |||||||
BINDING | 162 | 162 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105 | C | 1 |
Additional information
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Size range | 176-362 amino acids |
Related rules | None |
Fusion | None |