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HAMAP rule MF_00975

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General rule information [?]

Accession MF_00975
Dates 24-OCT-2013 (Created)
19-NOV-2022 (Last updated, Version 5)
Name Exosome_Csl4
Scope(s) Archaea
Template(s) Q980J9 (CSL4_SACS2); O30033 (CSL4_ARCFU); [ Recover all ]
Triggered by HAMAP; MF_00975 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CSL4
Protein name RecName: Full=Exosome complex component Csl4;
Gene name Name=csl4;

Comments [?]

FUNCTIONNon-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
SUBUNITComponent of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
SIMILARITYBelongs to the CSL4 family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding
end case
GO:0006401; Biological process:RNA catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS50126; S1; 1;
Pfam PF14382; ECR1_N; 1;
Pfam PF00575; S1; 1;
Pfam PF10447; EXOSC1; 1;

Features [?]

From: CSL4_ARCFU (O30033)
Key From To Description Tag Condition FTGroup
BINDING 143 143 /ligand="Zn(2+)"
C 1
BINDING 146 146 /ligand="Zn(2+)"
C 1
BINDING 159 159 /ligand="Zn(2+)"
C 1
BINDING 162 162 /ligand="Zn(2+)"
C 1

Additional information [?]

Size range 176-362 amino acids
Related rules None
Fusion Nter: None Cter: None

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