HAMAP rule MF_00977
General rule information
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| Accession | MF_00977 |
| Dates | 25-NOV-2013 (Created)
27-MAR-2023 (Last updated, Version 9) |
| Name | 3_5_Exoribonuc_actinobact |
| Scope(s) |
Bacteria Actinomycetota |
| Template(s) | P9WJ73 (EXRBN_MYCTU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00977 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | EXRBN |
| Protein name | RecName: Full=3'-5' exoribonuclease; EC=3.1.13.-; |
Comments
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| FUNCTION | Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. |
| case <FTTag:Mg> | |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Binds 1 Mg(2+) ion per subunit.; |
| end case | |
| SUBUNIT | Homodimer. |
Keywords
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| Exonuclease | |
| Hydrolase | |
| case <FTTag:Mg> | |
| Magnesium | |
| Metal-binding | |
| end case | |
| Nuclease | |
Gene Ontology
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| GO:0004532; Molecular function:RNA exonuclease activity | |
| case <FTTag:Mg> | |
| GO:0000287; Molecular function:magnesium ion binding | |
| end case | |
Cross-references
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Features
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| From: EXRBN_MYCTU (P9WJ73) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | 6 | 9 | /note="RNA binding" | D-[TS]-E-F | ||||||||
| BINDING | 6 | 6 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_note="catalytic" |
Mg | D | |||||||
Additional information
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| Size range | 150-200 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |